WW Domains [WW domény]

topical
Terms

WW doména

 

WW Domain

Definition

An approximately 40 amino acid protein domain that occurs in a variety of unrelated proteins and may be repeated up to four times in some proteins. It is characterized by two TRYPTOPHAN residues (WW) about 20 amino acids apart and folds into a stable triple-stranded BETA-SHEET. It binds PROLINE-RICH PROTEIN DOMAINS and PHOSPHOSERINE or PHOSPHOTHREONINE-containing protein domains that occur in many signal-transducing and cytoskeletal proteins such as DYSTROPHIN.

DUI
D000074585 MeSH Browser
CUI
M000627070
Previous indexing
Amino Acid Sequence (1996-2017); Protein Structure, Tertiary (1999-2017)
History note
2018
Public note
2018

G Phenomena and Processes
G02.111.570 Molecular Structure 1 313
G02.111.570.820 Molecular Conformation 228
G02.111.570.820.709 Protein Conformation 556
G02.111.570.820.709.275 Protein Structural Elements 1
G02.111.570.820.709.275.750 Protein Domains 178
G02.111.570.820.709.275.750.500 Protein Interaction Domains and Motifs 95
G02.111.570.820.709.275.750.500.080 Ankyrin Repeat 9
G02.111.570.820.709.275.750.500.290 B30.2-SPRY Domain
G02.111.570.820.709.275.750.500.343 BTB-POZ Domain
G02.111.570.820.709.275.750.500.395 Death Domain Superfamily
G02.111.570.820.709.275.750.500.422 FERM Domains 1
G02.111.570.820.709.275.750.500.448 Kelch Repeat 1
G02.111.570.820.709.275.750.500.474 MYND Domains
G02.111.570.820.709.275.750.500.500 PDZ Domains 2
G02.111.570.820.709.275.750.500.625 RING Finger Domains 1
G02.111.570.820.709.275.750.500.750 src Homology Domains 17
G02.111.570.820.709.275.750.500.813 Sterile Alpha Motif
G02.111.570.820.709.275.750.500.829 Tetratricopeptide Repeat
G02.111.570.820.709.275.750.500.844 Tudor Domain
G02.111.570.820.709.275.750.500.875 WD40 Repeats
G02.111.570.820.709.275.750.500.937 WW Domains