RING Finger Domains [domény RING-prstů]
- Terms
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doména RING-prstu
motiv RING-prstu
motivy RING-prstů
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RING Finger Motifs
A zinc-binding domain defined by the sequence Cysteine-X2-Cysteine-X(9-39)-Cysteine-X(l-3)-His-X(2-3)-Cysteine-X2-Cysteine -X(4-48)-Cysteine-X2-Cysteine, where X is any amino acid. The RING finger motif binds two atoms of zinc, with each zinc atom ligated tetrahedrally by either four cysteines or three cysteines and a histidine. The motif also forms into a unitary structure with a central cross-brace region and is found in many proteins that are involved in protein-protein interactions. The acronym RING stands for Really Interesting New Gene.
- DUI
- D054829 MeSH Browser
- CUI
- M0508104
- History note
- 2008
- Public note
- 2008
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