Zinc Fingers [zinkové prsty]

topical
28
Terms

DNA vazebné domény s motivem zinkových prstů
DNA vazebné domény se zinkovými prsty
DNA vazebné domény zinkových prstů
domény zinkových prstů vázající DNA
motiv zinkových prstů
motivy zinkových prstů
zinkový prst

 

Zinc Finger DNA-Binding Domains
Zinc Finger Motifs

Persistent link   https://www.medvik.cz/link/D016335
Definition

Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.

DUI
D016335 MeSH Browser
CUI
M0024968
Previous indexing
DNA-Binding Proteins (1987-1990); Amino Acid Sequence (1987-1990); Molecular Sequence Data (1988-1990)
History note
91
Public note
91

Allowable subheadings

DE
drug effects
GE
genetics 7
IM
immunology 4
PH
physiology 1
RE
radiation effects

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G02.111 Biochemical Phenomena 370
G02.111.570 Molecular Structure 1 314
G02.111.570.820 Molecular Conformation 228
G02.111.570.820.709 Protein Conformation 556
G02.111.570.820.709.275 Protein Structural Elements 1
G02.111.570.820.709.275.500 Amino Acid Motifs 101
G02.111.570.820.709.275.500.030 Ankyrin Repeat 9
G02.111.570.820.709.275.500.050 AT-Hook Motifs 1
G02.111.570.820.709.275.500.127 Cystine Knot Motifs
G02.111.570.820.709.275.500.205 F-Box Motifs
G02.111.570.820.709.275.500.360 Helix-Loop-Helix Motifs
G02.111.570.820.709.275.500.440 Immunoreceptor Tyrosine-Based Activation Motif
G02.111.570.820.709.275.500.480 Immunoreceptor Tyrosine-Based Inhibition Motif
G02.111.570.820.709.275.500.490 Kazal Motifs
G02.111.570.820.709.275.500.500 Kelch Repeat 1
G02.111.570.820.709.275.500.520 Leucine Zippers 4
G02.111.570.820.709.275.500.695 Poly-ADP-Ribose Binding Motif
G02.111.570.820.709.275.500.869 RNA-Binding Motifs
G02.111.570.820.709.275.500.898 Sterile Alpha Motif
G02.111.570.820.709.275.500.913 AAA Domain 1
G02.111.570.820.709.275.500.920 Tetratricopeptide Repeat
G02.111.570.820.709.275.500.927 WD40 Repeats
G02.111.570.820.709.275.500.985 Zinc Fingers 28
G02.111.570.820.709.275.500.985.250 CYS2-HIS2 Zinc Fingers
G02.111.570.820.709.275.500.985.375 MYND Domains
G02.111.570.820.709.275.500.985.438 PHD Zinc Fingers
G02.111.570.820.709.275.500.985.500 RING Finger Domains 1
G03 Metabolic Phenomena obsolete
G03 Metabolism 1 197
G04 Cell Physiological Phenomena 515
G05 Genetic Phenomena 135
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 17
G12 Immune System Phenomena 249
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 148
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 130
G17 Mathematical Concepts 66

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