Abuse-Deterrent Formulations [lékové formy zabraňující zneužití léčiv]

topical
Terms

abuse deterrent formulations
lékové formy omezující zneužití léčiv

 

Abuse-Deterrent Formulation

Persistent link   https://www.medvik.cz/link/D000075162
Definition

Drug formulations or delivery systems intended to discourage the abuse of CONTROLLED SUBSTANCES. These may include physical barriers to prevent chewing or crushing the drug; chemical barriers that prevent extraction of psychoactive ingredients; agonist-antagonist combinations to reduce euphoria associated with abuse; aversion, where controlled substances are combined with others that will produce an unpleasant effect if the patient manipulates the dosage form or exceeds the recommended dose; delivery systems that are resistant to abuse such as implants; or combinations of these methods.

DUI
D000075162 MeSH Browser
CUI
M000629657
History note
2018
Public note
2018

Allowable subheadings

AE
adverse effects 0
CL
classification 0
EC
economics 0
ES
ethics 0
HI
history 0
IS
instrumentation 0
MT
methods 0
MO
mortality 0
NU
nursing 0
PX
psychology 0
ST
standards 0
SN
statistics & numerical data 0
TD
trends 0
VE
veterinary 0

D Chemicals and Drugs
D26 Pharmaceutical Preparations 7 031
D26.255 Dosage Forms 1 499
D26.255.075 Abuse-Deterrent Formulations
D26.255.150 Capsules 99
D26.255.165 Colloids 183
D26.255.210 Delayed-Action Preparations 683
D26.255.260 Drug Carriers 507
D26.255.480 Liniments 7
D26.255.560 Micelles 98
D26.255.640 Ointments 548
D26.255.779 Powders 108
D26.255.785 Suppositories 123
D26.255.830 Tablets 419
D26.255.955 Vaginal Creams, Foams, and Jellies 40
D27 Chemical Actions and Uses 374
D27.505 Pharmacologic Actions 408
D27.505.696 Physiological Effects of Drugs 52
D27.505.696.034 Abuse-Deterrent Formulations
D27.505.696.034.500 Aversive Agents
D27.505.696.068 Antipyretics 106
D27.505.696.138 Antispermatogenic Agents 18
D27.505.696.207 Astringents 14
D27.505.696.242 Bone Density Conservation Agents 286
D27.505.696.260 Calcium-Regulating Hormones and Agents
D27.505.696.277 Central Nervous System Depressants 40
D27.505.696.282 Central Nervous System Stimulants 174
D27.505.696.305 Cerumenolytic Agents 1
D27.505.696.329 Emetics 12
D27.505.696.353 Endocrine Disruptors 176
D27.505.696.365 Galactogogues 3
D27.505.696.377 Growth Substances 288
D27.505.696.388 Hallucinogens 317
D27.505.696.399 Hormones, Hormone Substitutes, and Hormone Antagonists 43
D27.505.696.422 Hypoglycemic Agents 2 719
D27.505.696.477 Immunologic Factors 913
D27.505.696.494 Micronutrients 87
D27.505.696.510 Muscle Relaxants, Central 140
D27.505.696.543 Narcotic Antagonists 47
D27.505.696.560 Natriuretic Agents 8
D27.505.696.577 Neurotransmitter Agents 517
D27.505.696.620 Performance-Enhancing Substances 33
D27.505.696.663 Peripheral Nervous System Agents 5
D27.505.696.663.850 Sensory System Agents 12
D27.505.696.663.850.007 Abuse-Deterrent Formulations
D27.505.696.663.850.007.500 Aversive Agents
D27.505.696.663.850.014 Analgesics 1 829
D27.505.696.663.850.025 Anesthetics, Local 823
D27.505.696.663.850.512 Narcotic Antagonists 47
D27.505.696.706 Protective Agents 98
D27.505.696.875 Reproductive Control Agents 41
D27.505.696.937 Secretagogues 2
D27.505.954 Therapeutic Uses 61
D27.505.954.427 Central Nervous System Agents 231
D27.505.954.427.005 Abuse-Deterrent Formulations
D27.505.954.427.005.500 Aversive Agents
D27.505.954.427.010 Adjuvants, Anesthesia 37
D27.505.954.427.020 Alcohol Deterrents 96
D27.505.954.427.040 Analgesics 1 829
D27.505.954.427.080 Anticonvulsants 1 615
D27.505.954.427.090 Anti-Dyskinesia Agents 3
D27.505.954.427.095 Antiemetics 240
D27.505.954.427.153 Antitussive Agents 245
D27.505.954.427.210 Central Nervous System Depressants 40
D27.505.954.427.220 Central Nervous System Stimulants 174
D27.505.954.427.270 Emetics 12
D27.505.954.427.525 Muscle Relaxants, Central 140
D27.505.954.427.550 Narcotic Antagonists 47
D27.505.954.427.575 Neuroprotective Agents 384
D27.505.954.427.637 Nootropic Agents 162
D27.505.954.427.700 Psychotropic Drugs 1 531

E Analytical, Diagnostic and Therapeutic Techniques and Equipment
E02 Therapeutics 2 575
E02.319 Drug Therapy 10 521
E02.319.300 Drug Delivery Systems 694
E02.319.300.127 Abuse-Deterrent Formulations
E02.319.300.253 Delayed-Action Preparations 683
E02.319.300.380 Drug Carriers 507
E02.319.300.508 Insulin Infusion Systems 529
E02.319.300.754 Pharmaceutical Vehicles 45
E05 Investigative Techniques 209
E05.916 Technology, Pharmaceutical 920
E05.916.250 Dosage Forms 1 499
E05.916.250.500 Abuse-Deterrent Formulations

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