NEDD8 Protein [protein NEDD8]
- Terms
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NEDD8-protein podobný ubikvitinu
protein NEDD-8
ubikvitinu podobný protein NEDD8
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NEDD-8 Protein
Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8
Ubiquitin-like Protein NEDD8
A ubiquitin-like protein that functions in CELL CYCLE regulation and embryogenesis. It is attached covalently to its substrates following activation by the UBIQUITIN-ACTIVATING ENZYME E1-UBA3 enzyme complex. NEDD8 attaches to CULLINS, activating their E3 UBIQUITIN LIGASE activity, to promote polyubiquitination and degradation of CYCLINS and regulatory proteins
- DUI
- D000075687 MeSH Browser
- CUI
- M000631126
- Previous indexing
- Ubiquitins (1993-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 2
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
NED-8 protein, C elegans Chemical MeSH Browser
NEDD8 protein, human Chemical MeSH Browser
Nedd8 protein, Drosophila Chemical MeSH Browser
Nedd8 protein, mouse Chemical MeSH Browser