NEDD8 Protein [protein NEDD8]
topical
2
- Terms
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NEDD8-protein podobný ubikvitinu
protein NEDD-8
ubikvitinu podobný protein NEDD8
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NEDD-8 Protein
Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8
Ubiquitin-like Protein NEDD8
Persistent link
https://www.medvik.cz/link/D000075687
Definition
A ubiquitin-like protein that functions in CELL CYCLE regulation and embryogenesis. It is attached covalently to its substrates following activation by the UBIQUITIN-ACTIVATING ENZYME E1-UBA3 enzyme complex. NEDD8 attaches to CULLINS, activating their E3 UBIQUITIN LIGASE activity, to promote polyubiquitination and degradation of CYCLINS and regulatory proteins
- DUI
- D000075687 MeSH Browser
- CUI
- M000631126
- Previous indexing
- Ubiquitins (1993-2017)
- History note
- 2018
- Public note
- 2018
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Occurrences in Medvik records
D
Chemicals and Drugs