Cell Adhesion Molecule-1 [buněčná adhezní molekula 1]
- Terms
-
nádorový supresorový protein 1 plicního nádoru
protein CADM1
protein IGSF4
protein TSLC1
tumor-supresorový protein 1 plicního nádoru
-
CADM1 Protein
IGSF4 Protein
TSLC1 Protein
Tumor Suppressor in Lung Cancer 1 Protein
A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.
- DUI
- D000075982 MeSH Browser
- CUI
- M000631735
- Previous indexing
- Cell Adhesion Molecules (2000-2017); Immunoglobulins (2000-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 2
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 1
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0