A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.

DUI

D000077146 MeSH Prohlížeč

CUI

M0147530

CAS

(1,4'-Bipiperidine)-1'-carboxylic acid, (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester

Historická pozn.

2019 (1987)

Veřejná pozn.

2019; IRINOTECAN was indexed under CAMPTOTHECIN 1987-2018