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Calcitonin Gene-Related Peptide Receptor Antagonists [antagonisté CGRP receptorů]

topical
79
Terms

gepanty

 

Calcitonin Gene-Related Peptide Receptor Antagonist
CGRP Receptor Antagonist
CGRP Receptor Antagonists
CGRP-R Inhibitor
CGRP-R Inhibitors
GEPANT
GEPANTS

Persistent link   https://www.medvik.cz/link/D000077221
Definition

Pharmacologic agents that block NOCICEPTIVE PAIN signaling from CALCITONIN GENE-RELATED PEPTIDE RECEPTORS. They may be useful for the treatment of pain associated with MIGRAINE DISORDERS and OSTEOARTHRITIS.

DUI
D000077221 MeSH Browser
CUI
M000639812
History note
2019
Public note
2019

Allowable subheadings

AD
administration & dosage 24
AE
adverse effects 8
AN
analysis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification 5
EC
economics 2
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 1
PK
pharmacokinetics 5
PD
pharmacology 28
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 53
TO
toxicity
UR
urine

D Chemicals and Drugs
D27 Chemical Actions and Uses 374
D27.505 Pharmacologic Actions 410
D27.505.519 Molecular Mechanisms of Pharmacological Action 89
D27.505.519.124 Alkylating Agents 91
D27.505.519.143 Amylin Receptor Agonists
D27.505.519.162 Angiotensin Receptor Antagonists 225
D27.505.519.170 Antacids 162
D27.505.519.174 Antidiuretic Hormone Receptor Antagonists 28
D27.505.519.178 Antifoaming Agents 12
D27.505.519.182 Antiglycation Agents
D27.505.519.186 Antimetabolites 120
D27.505.519.217 Antioxidants 2 544
D27.505.519.241 Aversive Agents
D27.505.519.265 Bradykinin Receptor Antagonists 10
D27.505.519.270 Calcitonin Gene-Related Peptide Receptor Antagonists 79
D27.505.519.275 CCR5 Receptor Antagonists 4
D27.505.519.295 Cerumenolytic Agents 1
D27.505.519.334 Cystine Depleting Agents
D27.505.519.349 Cytochrome P-450 Enzyme Inducers 10
D27.505.519.364 Endothelin Receptor Antagonists 122
D27.505.519.374 Enzyme Activators 30
D27.505.519.389 Enzyme Inhibitors 887
D27.505.519.405 Enzyme Reactivators 16
D27.505.519.421 Fibrin Modulating Agents 2
D27.505.519.452 Heparin Antagonists 23
D27.505.519.507 Immune Checkpoint Inhibitors 393
D27.505.519.562 Membrane Transport Modulators 22
D27.505.519.593 Mitosis Modulators 3
D27.505.519.625 Neurotransmitter Agents 520
D27.505.519.656 Nitric Oxide Donors 63
D27.505.519.828 Peptidomimetics 11
D27.505.519.871 Radiopharmaceuticals 825
D27.505.519.914 Sequestering Agents 1
D27.505.519.936 Sodium-Glucose Transporter 2 Inhibitors 826
D27.505.519.947 Sphingosine 1 Phosphate Receptor Modulators 33
D27.505.519.952 Toll-Like Receptor Agonists
D27.505.519.957 Viral Fusion Protein Inhibitors
D27.505.696 Physiological Effects of Drugs 52
D27.505.696.663 Peripheral Nervous System Agents 5
D27.505.696.663.850 Sensory System Agents 12
D27.505.696.663.850.014 Analgesics 1 868
D27.505.696.663.850.014.040 Analgesics, Non-Narcotic 437
D27.505.696.663.850.014.580 Analgesics, Short-Acting 4
D27.505.696.663.850.014.610 Calcitonin Gene-Related Peptide Receptor Antagonists 79
D27.505.696.663.850.014.640 Dentin Desensitizing Agents 3
D27.505.696.663.850.014.760 Narcotics 419
D27.505.954 Therapeutic Uses 62
D27.505.954.427 Central Nervous System Agents 242
D27.505.954.427.040 Analgesics 1 868
D27.505.954.427.040.100 Analgesics, Non-Narcotic 437
D27.505.954.427.040.381 Analgesics, Short-Acting 4
D27.505.954.427.040.409 Calcitonin Gene-Related Peptide Receptor Antagonists 79
D27.505.954.427.040.437 Dentin Desensitizing Agents 3
D27.505.954.427.040.550 Narcotics 419

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