Exenatide [exenatid]
topical
64
- Terms
-
Byetta
exendin 4
-
AC 2993
AC 2993 LAR
Bydureon
Byetta
Ex4 Peptide
Exendin 4
Exendin-4
ITCA 650
Persistent link
https://www.medvik.cz/link/D000077270
Definition
A synthetic form of exendin-4, a 39-amino acid peptide isolated from the venom of the GILA MONSTER lizard (Heloderma suspectum). Exenatide increases CYCLIC AMP levels in pancreatic acinar cells and acts as a GLUCAGON-LIKE PEPTIDE-1 RECEPTOR (GLP-1) agonist and incretin mimetic, enhancing insulin secretion in response to increased glucose levels; it also suppresses inappropriate glucagon secretion and slows gastric emptying. It is used as an anti-diabetic and anti-obesity agent.
- DUI
- D000077270 MeSH Browser
- CUI
- M0199975
- History note
- 2019 (1992)
- Public note
- 2019; EXENATIDE was indexed under PEPTIDES and VENOMS 1992-2018
Allowable subheadings
- AD
- administration & dosage 17
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics 1
- PD
- pharmacology 7
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 14
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D12.644.132
Cystine-Knot Miniproteins
D12.644.136
Diazepam Binding Inhibitor
D12.644.138
Disintegrins
D12.644.173
Erabutoxins
D12.644.368
Mating Factor