Agammaglobulinaemia Tyrosine Kinase [proteinkinasa BTK]
topical
53
- Terms
-
Brutonova tyrosin kináza
Brutonova tyrosinkinasa
Brutonova tyrozinkináza
tyrosinová kináza BTK
-
B Cell Progenitor Kinase
Bruton's Tyrosine Kinase
Persistent link
https://www.medvik.cz/link/D000077329
Definition
A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA.
- DUI
- D000077329 MeSH Browser
- CUI
- M0219038
- History note
- 2019 (1993)
- Public note
- 2019; AGAMMAGLOBULINAEMIA TYROSINE KINASE was indexed under PROTEIN-TYROSINE KINASES 1993-2018
Allowable subheadings
- AD
- administration & dosage 1
- AE
- adverse effects 2
- AN
- analysis
- AI
- antagonists & inhibitors 46
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 3
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 4
- PK
- pharmacokinetics
- PD
- pharmacology 4
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 7
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.913.696.620.682.725.037
Dyrk Kinases
D08.811.913.696.620.682.725.300
Proto-Oncogene Proteins c-fes
D12.776.476.568.037
Dyrk Kinases
D12.776.476.568.300
Proto-Oncogene Proteins c-fes
BTK protein, human Chemical MeSH Browser
Btk protein, mouse Chemical MeSH Browser