mitogenem aktivované proteinkinasy kinas [Mitogen-Activated Protein Kinase Kinases]

tematický
41
Termíny

MAP kinasy kinas
MAP kinázy kináz
MAPK kinasy
MAPK kinázy
MAPK-ERK kinasy
MAPK-ERK kináza
MAPK-ERK kinázy
MAPKKs
MEKs
mitogenem aktivované proteinkinázy kináz

 

Map Kinase Kinase
MAP Kinase Kinases
MAP-ERK Kinase
MAPK Kinase
MAPK Kinases
MAPK-ERK Kinase
MAPK-ERK Kinases
MAPKK
MAPKKs
MEK
MEKs
Mitogen-Activated Protein Kinase Kinase

Perzistentní odkaz   https://www.medvik.cz/link/D020929
Definice

Rodina duálně specifických proteinkináz, jejíž členové jsou součástí proteinkinázových kaskád aktivovaných různými podněty. Tyto MAPK kinázy fosforylují mitogenem aktivované proteinkinázy a samy jsou fosforylovány MAP kináza kináza kinázami. Podrodinou jsou kinázy JNK (známé také jako kinázy SAPK).

A dual-specific protein kinase family whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES and are themselves phosphorylated by MAP KINASE KINASE KINASES. JNK kinases (also known as SAPK kinases) are a subfamily.

DUI
D020929 MeSH Prohlížeč
CUI
M0328038
Předchozí užití
Protein Kinases (1989-1999); Protein-Serine-Threonine Kinases (1993-1999); Protein-Tyrosine Kinase (1989-1999)
Historická pozn.
2000; for MAP-ERK KINASE use MEK1 PROTEIN (NM) 1992-1999
Veřejná pozn.
2000; MAP KINASE KINASE and MAPKK (now MITOGEN-ACTIVATED KINASE KINASES) were indexed under PROTEIN KINASES 1992-1999; MAP-ERK KINASE (now MITOGEN-ACTIVATED KINASE KINASES) was indexed under PROTEIN-TYROSINE KINASE 1992-1999

Povolená podhesla

AN
analýza 2
AI
antagonisté a inhibitory 16
AD
aplikace a dávkování 1
BI
biosyntéza
CS
chemická syntéza
CH
chemie
HI
dějiny
EC
ekonomika
PK
farmakokinetika 1
PD
farmakologie 1
PH
fyziologie 1
GE
genetika 4
IM
imunologie 1
IP
izolace a purifikace
CL
klasifikace
BL
krev
ME
metabolismus 10
UR
moč
CF
mozkomíšní mok
DF
nedostatek
ST
normy
PO
otrava
AE
škodlivé účinky 3
TU
terapeutické užití 8
TO
toxicita
DE
účinky léků 2
RE
účinky záření 1
UL
ultrastruktura
SD
zásobování a distribuce

D Chemikálie a léčiva
D08 enzymy a koenzymy 7
D08.811 enzymy 1 547
D08.811.913 transferasy 72
D08.811.913.696 fosfotransferasy 69
D08.811.913.696.620 fosfotransferasy s alkoholovou skupinou jako akceptorem 32
D08.811.913.696.620.682 proteinkinasy 248
D08.811.913.696.620.682.700 protein-serin-threoninkinasy 271
D08.811.913.696.620.682.700.062 aktivinové receptory 5
D08.811.913.696.620.682.700.074 kinasy AMP aktivovaných proteinkinas 1
D08.811.913.696.620.682.700.085 proteinkinasy aktivované AMP 41
D08.811.913.696.620.682.700.097 ATM protein 89
D08.811.913.696.620.682.700.103 kinasy Aurora 4
D08.811.913.696.620.682.700.108 homolog Atg1
D08.811.913.696.620.682.700.109 receptory kostního morfogenetického proteinu 3
D08.811.913.696.620.682.700.125 proteinkinasy závislé na vápníku a kalmodulinu 10
D08.811.913.696.620.682.700.140 kaseinkinasy 1
D08.811.913.696.620.682.700.143 checkpoint kinasa 1 19
D08.811.913.696.620.682.700.145 checkpoint kinasa 2 49
D08.811.913.696.620.682.700.150 cyklickými nukleotidy regulované proteinkinasy
D08.811.913.696.620.682.700.250 proteinkinasa aktivovaná DNA 14
D08.811.913.696.620.682.700.275 kinasy podobné doublecortinu
D08.811.913.696.620.682.700.288 kinasy Dyrk
D08.811.913.696.620.682.700.300 kinasa eIF-2 8
D08.811.913.696.620.682.700.364 kinasy receptorů spřažených s G-proteiny 2
D08.811.913.696.620.682.700.397 kinázy zárodečného centra 2
D08.811.913.696.620.682.700.429 kinasy glykogensynthasy
D08.811.913.696.620.682.700.494 kinasa I-kappa B 9
D08.811.913.696.620.682.700.526 kinázy asociované s receptory interleukinu-1 3
D08.811.913.696.620.682.700.534 LRRK2 2
D08.811.913.696.620.682.700.542 Lim-kinasy 2
D08.811.913.696.620.682.700.559 MAP kinasy kinas (kinas) 48
D08.811.913.696.620.682.700.565 mitogenem aktivované proteinkinasy kinas 41
D08.811.913.696.620.682.700.565.100 MAP kinasa-kinasa 1 29
D08.811.913.696.620.682.700.565.200 MAP kinasa-kinasa 2 24
D08.811.913.696.620.682.700.565.300 MAP kinasa-kinasa 3
D08.811.913.696.620.682.700.565.400 MAP kinasa-kinasa 4 6
D08.811.913.696.620.682.700.565.500 MAP kinasa-kinasa 5 2
D08.811.913.696.620.682.700.565.600 MAP kinasa-kinasa 6
D08.811.913.696.620.682.700.565.700 MAP kinasa-kinasa 7 1
D08.811.913.696.620.682.700.567 mitogenem aktivované proteinkinasy 100
D08.811.913.696.620.682.700.576 DM-kinasa 2
D08.811.913.696.620.682.700.579 kinasa indukující NF-kappaB 1
D08.811.913.696.620.682.700.581 kinasy NEK 4
D08.811.913.696.620.682.700.586 onkogenní protein v-akt 5
D08.811.913.696.620.682.700.596 p21 aktivované kinasy 9
D08.811.913.696.620.682.700.606 fytochrom A 2
D08.811.913.696.620.682.700.616 polo-like kinasy
D08.811.913.696.620.682.700.626 pozitivní transkripční elongační faktor b 4
D08.811.913.696.620.682.700.646 proteinkinasy řízené prolinem 1
D08.811.913.696.620.682.700.725 proteinkinasa C 138
D08.811.913.696.620.682.700.745 proteinkinasy PDK
D08.811.913.696.620.682.700.750 proteinkinasa D2
D08.811.913.696.620.682.700.755 protoonkogenní proteiny c-akt 117
D08.811.913.696.620.682.700.759 protoonkogenní proteiny c-bcr 19
D08.811.913.696.620.682.700.776 protoonkogenní proteiny c-pim-1 1
D08.811.913.696.620.682.700.783 PDH-kinasa
D08.811.913.696.620.682.700.789 TGF-beta receptor I. typu 2
D08.811.913.696.620.682.700.795 TGF-beta receptor II. typu
D08.811.913.696.620.682.700.801 serin-threoninkinasy interagující s receptory 7
D08.811.913.696.620.682.700.814 kinázy asociované s Rho 26
D08.811.913.696.620.682.700.862 kinasy ribozomálního proteinu S6 1
D08.811.913.696.620.682.700.897 serin-threoninkinasa 3
D08.811.913.696.620.682.700.931 TOR serin-threoninkinasy 193
D08.811.913.696.620.682.700.965 vakuolární třídící protein VPS15
D08.811.913.696.620.682.700.982 lysin-deficitní proteinkinasa WNK
D08.811.913.696.620.682.725 tyrosinkinasy 620
D08.811.913.696.620.682.725.025 proteinkinasa BTK 48
D08.811.913.696.620.682.725.037 kinasy Dyrk
D08.811.913.696.620.682.725.049 fokální adhezní tyrosinkinasy 9
D08.811.913.696.620.682.725.124 Janus kinasy 90
D08.811.913.696.620.682.725.200 mitogenem aktivované proteinkinasy kinas 41
D08.811.913.696.620.682.725.200.100 MAP kinasa-kinasa 1 29
D08.811.913.696.620.682.725.200.200 MAP kinasa-kinasa 2 24
D08.811.913.696.620.682.725.200.300 MAP kinasa-kinasa 3
D08.811.913.696.620.682.725.200.400 MAP kinasa-kinasa 4 6
D08.811.913.696.620.682.725.200.500 MAP kinasa-kinasa 5 2
D08.811.913.696.620.682.725.200.600 MAP kinasa-kinasa 6
D08.811.913.696.620.682.725.200.700 MAP kinasa-kinasa 7 1
D08.811.913.696.620.682.725.300 protoonkogenní proteiny c-fes
D08.811.913.696.620.682.725.400 tyrosinkinasové receptory 154
D08.811.913.696.620.682.725.500 protoonkogenní proteiny c-abl 7
D08.811.913.696.620.682.725.650 kinasa Syk 11
D08.811.913.696.620.682.725.800 skupina kinas odvozených od src-genu 50
D08.811.913.696.620.682.725.900 protein-tyrosinkináza ZAP-70 21
D12 aminokyseliny, peptidy a proteiny 16
D12.776 proteiny 2 577
D12.776.476 intracelulární signální peptidy a proteiny 174
D12.776.476.563 protein-serin-threoninkinasy 271
D12.776.476.563.062 aktivinové receptory 5
D12.776.476.563.074 kinasy AMP aktivovaných proteinkinas 1
D12.776.476.563.085 proteinkinasy aktivované AMP 41
D12.776.476.563.097 ATM protein 89
D12.776.476.563.103 kinasy Aurora 4
D12.776.476.563.108 homolog Atg1
D12.776.476.563.109 receptory kostního morfogenetického proteinu 3
D12.776.476.563.125 proteinkinasy závislé na vápníku a kalmodulinu 10
D12.776.476.563.140 kaseinkinasy 1
D12.776.476.563.143 checkpoint kinasa 1 19
D12.776.476.563.145 checkpoint kinasa 2 49
D12.776.476.563.150 cyklickými nukleotidy regulované proteinkinasy
D12.776.476.563.250 proteinkinasa aktivovaná DNA 14
D12.776.476.563.275 kinasy podobné doublecortinu
D12.776.476.563.288 kinasy Dyrk
D12.776.476.563.300 kinasa eIF-2 8
D12.776.476.563.364 kinasy receptorů spřažených s G-proteiny 2
D12.776.476.563.397 kinázy zárodečného centra 2
D12.776.476.563.429 kinasy glykogensynthasy
D12.776.476.563.494 kinasa I-kappa B 9
D12.776.476.563.526 kinázy asociované s receptory interleukinu-1 3
D12.776.476.563.534 LRRK2 2
D12.776.476.563.542 Lim-kinasy 2
D12.776.476.563.554 MAP kinasy kinas (kinas) 48
D12.776.476.563.565 mitogenem aktivované proteinkinasy kinas 41
D12.776.476.563.565.100 MAP kinasa-kinasa 1 29
D12.776.476.563.565.200 MAP kinasa-kinasa 2 24
D12.776.476.563.565.300 MAP kinasa-kinasa 3
D12.776.476.563.565.400 MAP kinasa-kinasa 4 6
D12.776.476.563.565.500 MAP kinasa-kinasa 5 2
D12.776.476.563.565.600 MAP kinasa-kinasa 6
D12.776.476.563.565.700 MAP kinasa-kinasa 7 1
D12.776.476.563.567 mitogenem aktivované proteinkinasy 100
D12.776.476.563.576 DM-kinasa 2
D12.776.476.563.579 kinasa indukující NF-kappaB 1
D12.776.476.563.581 kinasy NEK 4
D12.776.476.563.586 onkogenní protein v-akt 5
D12.776.476.563.596 p21 aktivované kinasy 9
D12.776.476.563.606 fytochrom A 2
D12.776.476.563.616 polo-like kinasy
D12.776.476.563.626 pozitivní transkripční elongační faktor b 4
D12.776.476.563.646 proteinkinasy řízené prolinem 1
D12.776.476.563.725 proteinkinasa C 138
D12.776.476.563.745 proteinkinasy PDK
D12.776.476.563.750 proteinkinasa D2
D12.776.476.563.755 protoonkogenní proteiny c-akt 117
D12.776.476.563.759 protoonkogenní proteiny c-bcr 19
D12.776.476.563.776 protoonkogenní proteiny c-pim-1 1
D12.776.476.563.783 PDH-kinasa
D12.776.476.563.789 TGF-beta receptor I. typu 2
D12.776.476.563.795 TGF-beta receptor II. typu
D12.776.476.563.801 serin-threoninkinasy interagující s receptory 7
D12.776.476.563.814 kinázy asociované s Rho 26
D12.776.476.563.862 kinasy ribozomálního proteinu S6 1
D12.776.476.563.897 serin-threoninkinasa 3
D12.776.476.563.931 TOR serin-threoninkinasy 193
D12.776.476.563.965 vakuolární třídící protein VPS15
D12.776.476.563.982 lysin-deficitní proteinkinasa WNK
D12.776.476.568 tyrosinkinasy 620
D12.776.476.568.025 proteinkinasa BTK 48
D12.776.476.568.037 kinasy Dyrk
D12.776.476.568.049 fokální adhezní tyrosinkinasy 9
D12.776.476.568.124 Janus kinasy 90
D12.776.476.568.200 mitogenem aktivované proteinkinasy kinas 41
D12.776.476.568.200.100 MAP kinasa-kinasa 1 29
D12.776.476.568.200.200 MAP kinasa-kinasa 2 24
D12.776.476.568.200.300 MAP kinasa-kinasa 3
D12.776.476.568.200.400 MAP kinasa-kinasa 4 6
D12.776.476.568.200.500 MAP kinasa-kinasa 5 2
D12.776.476.568.200.600 MAP kinasa-kinasa 6
D12.776.476.568.200.700 MAP kinasa-kinasa 7 1
D12.776.476.568.300 protoonkogenní proteiny c-fes
D12.776.476.568.400 tyrosinkinasové receptory 154
D12.776.476.568.500 protoonkogenní proteiny c-abl 7
D12.776.476.568.650 kinasa Syk 11
D12.776.476.568.800 skupina kinas odvozených od src-genu 50
D12.776.476.568.900 protein-tyrosinkináza ZAP-70 21

AT1G32320 protein, Arabidopsis Chemical MeSH Prohlížeč

AtMPK3 protein, Arabidopsis Chemical MeSH Prohlížeč

BCK1 protein, S cerevisiae Chemical MeSH Prohlížeč

DdMEK1 protein, Dictyostelium discoideum Chemical MeSH Prohlížeč

Fuz7 protein, Ustilago maydis Chemical MeSH Prohlížeč

HST7 protein, Candida albicans Chemical MeSH Prohlížeč

Hep protein, Drosophila Chemical MeSH Prohlížeč

Lk6 protein, Drosophila Chemical MeSH Prohlížeč

MAP kinase kinase ubc5 Chemical MeSH Prohlížeč

MAP2K9 protein, Arabidopsis Chemical MeSH Prohlížeč

MKK1 protein, S cerevisiae Chemical MeSH Prohlížeč

MKK2 protein, Arabidopsis Chemical MeSH Prohlížeč

MKK2 protein, S cerevisiae Chemical MeSH Prohlížeč

MKK4 protein, Arabidopsis Chemical MeSH Prohlížeč

MKK5 protein, Arabidopsis Chemical MeSH Prohlížeč

MKK9 protein, Arabidopsis Chemical MeSH Prohlížeč

MKKK20 protein, Arabidopsis Chemical MeSH Prohlížeč

PBK protein, Xenopus Chemical MeSH Prohlížeč

PBS2 protein, S cerevisiae Chemical MeSH Prohlížeč

PDZ-binding kinase Chemical MeSH Prohlížeč

PK7 protein, Plasmodium falciparum Chemical MeSH Prohlížeč

Pbk protein, rat Chemical MeSH Prohlížeč

SIMKK protein, Medicago sativa Chemical MeSH Prohlížeč

STE7 protein, S cerevisiae Chemical MeSH Prohlížeč

TOPK protein, mouse Chemical MeSH Prohlížeč

salicylic acid-induced protein kinase kinase Chemical MeSH Prohlížeč

win1 protein, S pombe Chemical MeSH Prohlížeč

wis1 protein, S pombe Chemical MeSH Prohlížeč

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