Mitogen-Activated Protein Kinase Kinases [mitogenem aktivované proteinkinasy kinas]

topical
41
Terms

MAP kinasy kinas
MAP kinázy kináz
MAPK kinasy
MAPK kinázy
MAPK-ERK kinasy
MAPK-ERK kináza
MAPK-ERK kinázy
MAPKKs
MEKs
mitogenem aktivované proteinkinázy kináz

 

Map Kinase Kinase
MAP Kinase Kinases
MAP-ERK Kinase
MAPK Kinase
MAPK Kinases
MAPK-ERK Kinase
MAPK-ERK Kinases
MAPKK
MAPKKs
MEK
MEKs
Mitogen-Activated Protein Kinase Kinase

Persistent link   https://www.medvik.cz/link/D020929
Definition

A dual-specific protein kinase family whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES and are themselves phosphorylated by MAP KINASE KINASE KINASES. JNK kinases (also known as SAPK kinases) are a subfamily.

DUI
D020929 MeSH Browser
CUI
M0328038
Previous indexing
Protein Kinases (1989-1999); Protein-Serine-Threonine Kinases (1993-1999); Protein-Tyrosine Kinase (1989-1999)
History note
2000; for MAP-ERK KINASE use MEK1 PROTEIN (NM) 1992-1999
Public note
2000; MAP KINASE KINASE and MAPKK (now MITOGEN-ACTIVATED KINASE KINASES) were indexed under PROTEIN KINASES 1992-1999; MAP-ERK KINASE (now MITOGEN-ACTIVATED KINASE KINASES) was indexed under PROTEIN-TYROSINE KINASE 1992-1999

Allowable subheadings

AD
administration & dosage 1
AE
adverse effects 3
AN
analysis 2
AI
antagonists & inhibitors 16
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects 2
EC
economics
GE
genetics 4
HI
history
IM
immunology 1
IP
isolation & purification
ME
metabolism 10
PK
pharmacokinetics 1
PD
pharmacology 1
PH
physiology 1
PO
poisoning
RE
radiation effects 1
ST
standards
SD
supply & distribution
TU
therapeutic use 8
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 551
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.620 Phosphotransferases (Alcohol Group Acceptor) 32
D08.811.913.696.620.682 Protein Kinases 249
D08.811.913.696.620.682.700 Protein Serine-Threonine Kinases 273
D08.811.913.696.620.682.700.062 Activin Receptors 5
D08.811.913.696.620.682.700.074 AMP-Activated Protein Kinase Kinases 1
D08.811.913.696.620.682.700.085 AMP-Activated Protein Kinases 41
D08.811.913.696.620.682.700.097 Ataxia Telangiectasia Mutated Proteins 89
D08.811.913.696.620.682.700.103 Aurora Kinases 4
D08.811.913.696.620.682.700.108 Autophagy-Related Protein-1 Homolog 1
D08.811.913.696.620.682.700.109 Bone Morphogenetic Protein Receptors 3
D08.811.913.696.620.682.700.125 Calcium-Calmodulin-Dependent Protein Kinases 10
D08.811.913.696.620.682.700.140 Casein Kinases 1
D08.811.913.696.620.682.700.143 Checkpoint Kinase 1 20
D08.811.913.696.620.682.700.145 Checkpoint Kinase 2 50
D08.811.913.696.620.682.700.150 Cyclic Nucleotide-Regulated Protein Kinases
D08.811.913.696.620.682.700.250 DNA-Activated Protein Kinase 14
D08.811.913.696.620.682.700.275 Doublecortin-Like Kinases
D08.811.913.696.620.682.700.288 Dyrk Kinases
D08.811.913.696.620.682.700.300 eIF-2 Kinase 8
D08.811.913.696.620.682.700.364 G-Protein-Coupled Receptor Kinases 2
D08.811.913.696.620.682.700.397 Germinal Center Kinases 2
D08.811.913.696.620.682.700.429 Glycogen Synthase Kinases
D08.811.913.696.620.682.700.494 I-kappa B Kinase 9
D08.811.913.696.620.682.700.526 Interleukin-1 Receptor-Associated Kinases 3
D08.811.913.696.620.682.700.534 Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 2
D08.811.913.696.620.682.700.542 Lim Kinases 2
D08.811.913.696.620.682.700.559 MAP Kinase Kinase Kinases 48
D08.811.913.696.620.682.700.565 Mitogen-Activated Protein Kinase Kinases 41
D08.811.913.696.620.682.700.565.100 MAP Kinase Kinase 1 29
D08.811.913.696.620.682.700.565.200 MAP Kinase Kinase 2 24
D08.811.913.696.620.682.700.565.300 MAP Kinase Kinase 3
D08.811.913.696.620.682.700.565.400 MAP Kinase Kinase 4 6
D08.811.913.696.620.682.700.565.500 MAP Kinase Kinase 5 2
D08.811.913.696.620.682.700.565.600 MAP Kinase Kinase 6
D08.811.913.696.620.682.700.565.700 MAP Kinase Kinase 7 1
D08.811.913.696.620.682.700.567 Mitogen-Activated Protein Kinases 101
D08.811.913.696.620.682.700.576 Myotonin-Protein Kinase 2
D08.811.913.696.620.682.700.579 NF-kappaB-Inducing Kinase 1
D08.811.913.696.620.682.700.581 NIMA-Related Kinases 4
D08.811.913.696.620.682.700.586 Oncogene Protein v-akt 5
D08.811.913.696.620.682.700.596 p21-Activated Kinases 9
D08.811.913.696.620.682.700.606 Phytochrome A 2
D08.811.913.696.620.682.700.616 Polo-like Kinases
D08.811.913.696.620.682.700.626 Positive Transcriptional Elongation Factor B 4
D08.811.913.696.620.682.700.646 Proline-Directed Protein Kinases 1
D08.811.913.696.620.682.700.725 Protein Kinase C 138
D08.811.913.696.620.682.700.745 3-Phosphoinositide-Dependent Protein Kinases
D08.811.913.696.620.682.700.750 Protein Kinase D2
D08.811.913.696.620.682.700.755 Proto-Oncogene Proteins c-akt 120
D08.811.913.696.620.682.700.759 Proto-Oncogene Proteins c-bcr 19
D08.811.913.696.620.682.700.776 Proto-Oncogene Proteins c-pim-1 1
D08.811.913.696.620.682.700.783 Pyruvate Dehydrogenase Acetyl-Transferring Kinase 1
D08.811.913.696.620.682.700.789 Receptor, Transforming Growth Factor-beta Type I 2
D08.811.913.696.620.682.700.795 Receptor, Transforming Growth Factor-beta Type II
D08.811.913.696.620.682.700.801 Receptor-Interacting Protein Serine-Threonine Kinases 7
D08.811.913.696.620.682.700.814 rho-Associated Kinases 26
D08.811.913.696.620.682.700.862 Ribosomal Protein S6 Kinases 1
D08.811.913.696.620.682.700.897 Serine-Threonine Kinase 3
D08.811.913.696.620.682.700.931 TOR Serine-Threonine Kinases 196
D08.811.913.696.620.682.700.965 Vacuolar Sorting Protein VPS15
D08.811.913.696.620.682.700.982 WNK Lysine-Deficient Protein Kinase 1
D08.811.913.696.620.682.725 Protein-Tyrosine Kinases 622
D08.811.913.696.620.682.725.025 Agammaglobulinaemia Tyrosine Kinase 53
D08.811.913.696.620.682.725.037 Dyrk Kinases
D08.811.913.696.620.682.725.049 Focal Adhesion Protein-Tyrosine Kinases 9
D08.811.913.696.620.682.725.124 Janus Kinases 90
D08.811.913.696.620.682.725.200 Mitogen-Activated Protein Kinase Kinases 41
D08.811.913.696.620.682.725.200.100 MAP Kinase Kinase 1 29
D08.811.913.696.620.682.725.200.200 MAP Kinase Kinase 2 24
D08.811.913.696.620.682.725.200.300 MAP Kinase Kinase 3
D08.811.913.696.620.682.725.200.400 MAP Kinase Kinase 4 6
D08.811.913.696.620.682.725.200.500 MAP Kinase Kinase 5 2
D08.811.913.696.620.682.725.200.600 MAP Kinase Kinase 6
D08.811.913.696.620.682.725.200.700 MAP Kinase Kinase 7 1
D08.811.913.696.620.682.725.300 Proto-Oncogene Proteins c-fes
D08.811.913.696.620.682.725.400 Receptor Protein-Tyrosine Kinases 154
D08.811.913.696.620.682.725.500 Proto-Oncogene Proteins c-abl 7
D08.811.913.696.620.682.725.650 Syk Kinase 11
D08.811.913.696.620.682.725.800 src-Family Kinases 50
D08.811.913.696.620.682.725.900 ZAP-70 Protein-Tyrosine Kinase 21
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 581
D12.776.476 Intracellular Signaling Peptides and Proteins 175
D12.776.476.563 Protein Serine-Threonine Kinases 273
D12.776.476.563.062 Activin Receptors 5
D12.776.476.563.074 AMP-Activated Protein Kinase Kinases 1
D12.776.476.563.085 AMP-Activated Protein Kinases 41
D12.776.476.563.097 Ataxia Telangiectasia Mutated Proteins 89
D12.776.476.563.103 Aurora Kinases 4
D12.776.476.563.108 Autophagy-Related Protein-1 Homolog 1
D12.776.476.563.109 Bone Morphogenetic Protein Receptors 3
D12.776.476.563.125 Calcium-Calmodulin-Dependent Protein Kinases 10
D12.776.476.563.140 Casein Kinases 1
D12.776.476.563.143 Checkpoint Kinase 1 20
D12.776.476.563.145 Checkpoint Kinase 2 50
D12.776.476.563.150 Cyclic Nucleotide-Regulated Protein Kinases
D12.776.476.563.250 DNA-Activated Protein Kinase 14
D12.776.476.563.275 Doublecortin-Like Kinases
D12.776.476.563.288 Dyrk Kinases
D12.776.476.563.300 eIF-2 Kinase 8
D12.776.476.563.364 G-Protein-Coupled Receptor Kinases 2
D12.776.476.563.397 Germinal Center Kinases 2
D12.776.476.563.429 Glycogen Synthase Kinases
D12.776.476.563.494 I-kappa B Kinase 9
D12.776.476.563.526 Interleukin-1 Receptor-Associated Kinases 3
D12.776.476.563.534 Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 2
D12.776.476.563.542 Lim Kinases 2
D12.776.476.563.554 MAP Kinase Kinase Kinases 48
D12.776.476.563.565 Mitogen-Activated Protein Kinase Kinases 41
D12.776.476.563.565.100 MAP Kinase Kinase 1 29
D12.776.476.563.565.200 MAP Kinase Kinase 2 24
D12.776.476.563.565.300 MAP Kinase Kinase 3
D12.776.476.563.565.400 MAP Kinase Kinase 4 6
D12.776.476.563.565.500 MAP Kinase Kinase 5 2
D12.776.476.563.565.600 MAP Kinase Kinase 6
D12.776.476.563.565.700 MAP Kinase Kinase 7 1
D12.776.476.563.567 Mitogen-Activated Protein Kinases 101
D12.776.476.563.576 Myotonin-Protein Kinase 2
D12.776.476.563.579 NF-kappaB-Inducing Kinase 1
D12.776.476.563.581 NIMA-Related Kinases 4
D12.776.476.563.586 Oncogene Protein v-akt 5
D12.776.476.563.596 p21-Activated Kinases 9
D12.776.476.563.606 Phytochrome A 2
D12.776.476.563.616 Polo-like Kinases
D12.776.476.563.626 Positive Transcriptional Elongation Factor B 4
D12.776.476.563.646 Proline-Directed Protein Kinases 1
D12.776.476.563.725 Protein Kinase C 138
D12.776.476.563.745 3-Phosphoinositide-Dependent Protein Kinases
D12.776.476.563.750 Protein Kinase D2
D12.776.476.563.755 Proto-Oncogene Proteins c-akt 120
D12.776.476.563.759 Proto-Oncogene Proteins c-bcr 19
D12.776.476.563.776 Proto-Oncogene Proteins c-pim-1 1
D12.776.476.563.783 Pyruvate Dehydrogenase Acetyl-Transferring Kinase 1
D12.776.476.563.789 Receptor, Transforming Growth Factor-beta Type I 2
D12.776.476.563.795 Receptor, Transforming Growth Factor-beta Type II
D12.776.476.563.801 Receptor-Interacting Protein Serine-Threonine Kinases 7
D12.776.476.563.814 rho-Associated Kinases 26
D12.776.476.563.862 Ribosomal Protein S6 Kinases 1
D12.776.476.563.897 Serine-Threonine Kinase 3
D12.776.476.563.931 TOR Serine-Threonine Kinases 196
D12.776.476.563.965 Vacuolar Sorting Protein VPS15
D12.776.476.563.982 WNK Lysine-Deficient Protein Kinase 1
D12.776.476.568 Protein-Tyrosine Kinases 622
D12.776.476.568.025 Agammaglobulinaemia Tyrosine Kinase 53
D12.776.476.568.037 Dyrk Kinases
D12.776.476.568.049 Focal Adhesion Protein-Tyrosine Kinases 9
D12.776.476.568.124 Janus Kinases 90
D12.776.476.568.200 Mitogen-Activated Protein Kinase Kinases 41
D12.776.476.568.200.100 MAP Kinase Kinase 1 29
D12.776.476.568.200.200 MAP Kinase Kinase 2 24
D12.776.476.568.200.300 MAP Kinase Kinase 3
D12.776.476.568.200.400 MAP Kinase Kinase 4 6
D12.776.476.568.200.500 MAP Kinase Kinase 5 2
D12.776.476.568.200.600 MAP Kinase Kinase 6
D12.776.476.568.200.700 MAP Kinase Kinase 7 1
D12.776.476.568.300 Proto-Oncogene Proteins c-fes
D12.776.476.568.400 Receptor Protein-Tyrosine Kinases 154
D12.776.476.568.500 Proto-Oncogene Proteins c-abl 7
D12.776.476.568.650 Syk Kinase 11
D12.776.476.568.800 src-Family Kinases 50
D12.776.476.568.900 ZAP-70 Protein-Tyrosine Kinase 21

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