mitogenem aktivované proteinkinasy kinas [Mitogen-Activated Protein Kinase Kinases]

tematický
40
Termíny

MAP kinasy kinas
MAP kinázy kináz
MAPK kinasy
MAPK kinázy
MAPK-ERK kinasy
MAPK-ERK kináza
MAPK-ERK kinázy
MAPKKs
MEKs
mitogenem aktivované proteinkinázy kináz

 

Map Kinase Kinase
MAP Kinase Kinases
MAP-ERK Kinase
MAPK Kinase
MAPK Kinases
MAPK-ERK Kinase
MAPK-ERK Kinases
MAPKK
MAPKKs
MEK
MEKs
Mitogen-Activated Protein Kinase Kinase

Perzistentní odkaz   https://www.medvik.cz/link/D020929
Definice

Rodina duálně specifických proteinkináz, jejíž členové jsou součástí proteinkinázových kaskád aktivovaných různými podněty. Tyto MAPK kinázy fosforylují mitogenem aktivované proteinkinázy a samy jsou fosforylovány MAP kináza kináza kinázami. Podrodinou jsou kinázy JNK (známé také jako kinázy SAPK).

A dual-specific protein kinase family whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES and are themselves phosphorylated by MAP KINASE KINASE KINASES. JNK kinases (also known as SAPK kinases) are a subfamily.

DUI
D020929 MeSH Prohlížeč
CUI
M0328038
Předchozí užití
Protein Kinases (1989-1999); Protein-Serine-Threonine Kinases (1993-1999); Protein-Tyrosine Kinase (1989-1999)
Historická pozn.
2000; for MAP-ERK KINASE use MEK1 PROTEIN (NM) 1992-1999
Veřejná pozn.
2000; MAP KINASE KINASE and MAPKK (now MITOGEN-ACTIVATED KINASE KINASES) were indexed under PROTEIN KINASES 1992-1999; MAP-ERK KINASE (now MITOGEN-ACTIVATED KINASE KINASES) was indexed under PROTEIN-TYROSINE KINASE 1992-1999

Povolená podhesla

AN
analýza 2
AI
antagonisté a inhibitory 15
AD
aplikace a dávkování 1
BI
biosyntéza 0
CS
chemická syntéza 0
CH
chemie 0
HI
dějiny 0
EC
ekonomika 0
PK
farmakokinetika 1
PD
farmakologie 1
PH
fyziologie 1
GE
genetika 4
IM
imunologie 1
IP
izolace a purifikace 0
CL
klasifikace 0
BL
krev 0
ME
metabolismus 10
UR
moč 0
CF
mozkomíšní mok 0
DF
nedostatek 0
ST
normy 0
PO
otrava 0
AE
škodlivé účinky 3
TU
terapeutické užití 7
TO
toxicita 0
DE
účinky léků 2
RE
účinky záření 1
UL
ultrastruktura 0
SD
zásobování a distribuce 0

D Chemikálie a léčiva
D08 enzymy a koenzymy 7
D08.811 enzymy 1 547
D08.811.913 transferasy 72
D08.811.913.696 fosfotransferasy 69
D08.811.913.696.620 fosfotransferasy s alkoholovou skupinou jako akceptorem 32
D08.811.913.696.620.682 proteinkinasy 248
D08.811.913.696.620.682.700 protein-serin-threoninkinasy 271
D08.811.913.696.620.682.700.062 aktivinové receptory 5
D08.811.913.696.620.682.700.074 kinasy AMP aktivovaných proteinkinas 1
D08.811.913.696.620.682.700.085 proteinkinasy aktivované AMP 41
D08.811.913.696.620.682.700.097 ATM protein 89
D08.811.913.696.620.682.700.103 kinasy Aurora 4
D08.811.913.696.620.682.700.108 homolog Atg1
D08.811.913.696.620.682.700.109 receptory kostního morfogenetického proteinu 3
D08.811.913.696.620.682.700.125 proteinkinasy závislé na vápníku a kalmodulinu 10
D08.811.913.696.620.682.700.140 kaseinkinasy 1
D08.811.913.696.620.682.700.143 checkpoint kinasa 1 19
D08.811.913.696.620.682.700.145 checkpoint kinasa 2 49
D08.811.913.696.620.682.700.150 cyklickými nukleotidy regulované proteinkinasy
D08.811.913.696.620.682.700.250 proteinkinasa aktivovaná DNA 14
D08.811.913.696.620.682.700.275 kinasy podobné doublecortinu
D08.811.913.696.620.682.700.288 kinasy Dyrk
D08.811.913.696.620.682.700.300 kinasa eIF-2 8
D08.811.913.696.620.682.700.364 kinasy receptorů spřažených s G-proteiny 2
D08.811.913.696.620.682.700.397 kinázy zárodečného centra 2
D08.811.913.696.620.682.700.429 kinasy glykogensynthasy
D08.811.913.696.620.682.700.494 kinasa I-kappa B 9
D08.811.913.696.620.682.700.526 kinázy asociované s receptory interleukinu-1 3
D08.811.913.696.620.682.700.534 LRRK2 2
D08.811.913.696.620.682.700.542 Lim-kinasy 2
D08.811.913.696.620.682.700.559 MAP kinasy kinas (kinas) 48
D08.811.913.696.620.682.700.565 mitogenem aktivované proteinkinasy kinas 40
D08.811.913.696.620.682.700.565.100 MAP kinasa-kinasa 1 29
D08.811.913.696.620.682.700.565.200 MAP kinasa-kinasa 2 24
D08.811.913.696.620.682.700.565.300 MAP kinasa-kinasa 3
D08.811.913.696.620.682.700.565.400 MAP kinasa-kinasa 4 6
D08.811.913.696.620.682.700.565.500 MAP kinasa-kinasa 5 2
D08.811.913.696.620.682.700.565.600 MAP kinasa-kinasa 6
D08.811.913.696.620.682.700.565.700 MAP kinasa-kinasa 7 1
D08.811.913.696.620.682.700.567 mitogenem aktivované proteinkinasy 100
D08.811.913.696.620.682.700.576 DM-kinasa 2
D08.811.913.696.620.682.700.579 kinasa indukující NF-kappaB 1
D08.811.913.696.620.682.700.581 kinasy NEK 4
D08.811.913.696.620.682.700.586 onkogenní protein v-akt 5
D08.811.913.696.620.682.700.596 p21 aktivované kinasy 9
D08.811.913.696.620.682.700.606 fytochrom A 2
D08.811.913.696.620.682.700.616 polo-like kinasy
D08.811.913.696.620.682.700.626 pozitivní transkripční elongační faktor b 4
D08.811.913.696.620.682.700.646 proteinkinasy řízené prolinem 1
D08.811.913.696.620.682.700.725 proteinkinasa C 138
D08.811.913.696.620.682.700.745 proteinkinasy PDK
D08.811.913.696.620.682.700.750 proteinkinasa D2
D08.811.913.696.620.682.700.755 protoonkogenní proteiny c-akt 116
D08.811.913.696.620.682.700.759 protoonkogenní proteiny c-bcr 19
D08.811.913.696.620.682.700.776 protoonkogenní proteiny c-pim-1 1
D08.811.913.696.620.682.700.783 PDH-kinasa
D08.811.913.696.620.682.700.789 TGF-beta receptor I. typu 2
D08.811.913.696.620.682.700.795 TGF-beta receptor II. typu
D08.811.913.696.620.682.700.801 serin-threoninkinasy interagující s receptory 7
D08.811.913.696.620.682.700.814 kinázy asociované s Rho 26
D08.811.913.696.620.682.700.862 kinasy ribozomálního proteinu S6 1
D08.811.913.696.620.682.700.897 serin-threoninkinasa 3
D08.811.913.696.620.682.700.931 TOR serin-threoninkinasy 193
D08.811.913.696.620.682.700.965 vakuolární třídící protein VPS15
D08.811.913.696.620.682.700.982 lysin-deficitní proteinkinasa WNK
D08.811.913.696.620.682.725 tyrosinkinasy 620
D08.811.913.696.620.682.725.025 proteinkinasa BTK 47
D08.811.913.696.620.682.725.037 kinasy Dyrk
D08.811.913.696.620.682.725.049 fokální adhezní tyrosinkinasy 9
D08.811.913.696.620.682.725.124 Janus kinasy 90
D08.811.913.696.620.682.725.200 mitogenem aktivované proteinkinasy kinas 40
D08.811.913.696.620.682.725.200.100 MAP kinasa-kinasa 1 29
D08.811.913.696.620.682.725.200.200 MAP kinasa-kinasa 2 24
D08.811.913.696.620.682.725.200.300 MAP kinasa-kinasa 3
D08.811.913.696.620.682.725.200.400 MAP kinasa-kinasa 4 6
D08.811.913.696.620.682.725.200.500 MAP kinasa-kinasa 5 2
D08.811.913.696.620.682.725.200.600 MAP kinasa-kinasa 6
D08.811.913.696.620.682.725.200.700 MAP kinasa-kinasa 7 1
D08.811.913.696.620.682.725.300 protoonkogenní proteiny c-fes
D08.811.913.696.620.682.725.400 tyrosinkinasové receptory 148
D08.811.913.696.620.682.725.500 protoonkogenní proteiny c-abl 7
D08.811.913.696.620.682.725.650 kinasa Syk 11
D08.811.913.696.620.682.725.800 skupina kinas odvozených od src-genu 50
D08.811.913.696.620.682.725.900 protein-tyrosinkináza ZAP-70 21
D12 aminokyseliny, peptidy a proteiny 16
D12.776 proteiny 2 575
D12.776.476 intracelulární signální peptidy a proteiny 174
D12.776.476.563 protein-serin-threoninkinasy 271
D12.776.476.563.062 aktivinové receptory 5
D12.776.476.563.074 kinasy AMP aktivovaných proteinkinas 1
D12.776.476.563.085 proteinkinasy aktivované AMP 41
D12.776.476.563.097 ATM protein 89
D12.776.476.563.103 kinasy Aurora 4
D12.776.476.563.108 homolog Atg1
D12.776.476.563.109 receptory kostního morfogenetického proteinu 3
D12.776.476.563.125 proteinkinasy závislé na vápníku a kalmodulinu 10
D12.776.476.563.140 kaseinkinasy 1
D12.776.476.563.143 checkpoint kinasa 1 19
D12.776.476.563.145 checkpoint kinasa 2 49
D12.776.476.563.150 cyklickými nukleotidy regulované proteinkinasy
D12.776.476.563.250 proteinkinasa aktivovaná DNA 14
D12.776.476.563.275 kinasy podobné doublecortinu
D12.776.476.563.288 kinasy Dyrk
D12.776.476.563.300 kinasa eIF-2 8
D12.776.476.563.364 kinasy receptorů spřažených s G-proteiny 2
D12.776.476.563.397 kinázy zárodečného centra 2
D12.776.476.563.429 kinasy glykogensynthasy
D12.776.476.563.494 kinasa I-kappa B 9
D12.776.476.563.526 kinázy asociované s receptory interleukinu-1 3
D12.776.476.563.534 LRRK2 2
D12.776.476.563.542 Lim-kinasy 2
D12.776.476.563.554 MAP kinasy kinas (kinas) 48
D12.776.476.563.565 mitogenem aktivované proteinkinasy kinas 40
D12.776.476.563.565.100 MAP kinasa-kinasa 1 29
D12.776.476.563.565.200 MAP kinasa-kinasa 2 24
D12.776.476.563.565.300 MAP kinasa-kinasa 3
D12.776.476.563.565.400 MAP kinasa-kinasa 4 6
D12.776.476.563.565.500 MAP kinasa-kinasa 5 2
D12.776.476.563.565.600 MAP kinasa-kinasa 6
D12.776.476.563.565.700 MAP kinasa-kinasa 7 1
D12.776.476.563.567 mitogenem aktivované proteinkinasy 100
D12.776.476.563.576 DM-kinasa 2
D12.776.476.563.579 kinasa indukující NF-kappaB 1
D12.776.476.563.581 kinasy NEK 4
D12.776.476.563.586 onkogenní protein v-akt 5
D12.776.476.563.596 p21 aktivované kinasy 9
D12.776.476.563.606 fytochrom A 2
D12.776.476.563.616 polo-like kinasy
D12.776.476.563.626 pozitivní transkripční elongační faktor b 4
D12.776.476.563.646 proteinkinasy řízené prolinem 1
D12.776.476.563.725 proteinkinasa C 138
D12.776.476.563.745 proteinkinasy PDK
D12.776.476.563.750 proteinkinasa D2
D12.776.476.563.755 protoonkogenní proteiny c-akt 116
D12.776.476.563.759 protoonkogenní proteiny c-bcr 19
D12.776.476.563.776 protoonkogenní proteiny c-pim-1 1
D12.776.476.563.783 PDH-kinasa
D12.776.476.563.789 TGF-beta receptor I. typu 2
D12.776.476.563.795 TGF-beta receptor II. typu
D12.776.476.563.801 serin-threoninkinasy interagující s receptory 7
D12.776.476.563.814 kinázy asociované s Rho 26
D12.776.476.563.862 kinasy ribozomálního proteinu S6 1
D12.776.476.563.897 serin-threoninkinasa 3
D12.776.476.563.931 TOR serin-threoninkinasy 193
D12.776.476.563.965 vakuolární třídící protein VPS15
D12.776.476.563.982 lysin-deficitní proteinkinasa WNK
D12.776.476.568 tyrosinkinasy 620
D12.776.476.568.025 proteinkinasa BTK 47
D12.776.476.568.037 kinasy Dyrk
D12.776.476.568.049 fokální adhezní tyrosinkinasy 9
D12.776.476.568.124 Janus kinasy 90
D12.776.476.568.200 mitogenem aktivované proteinkinasy kinas 40
D12.776.476.568.200.100 MAP kinasa-kinasa 1 29
D12.776.476.568.200.200 MAP kinasa-kinasa 2 24
D12.776.476.568.200.300 MAP kinasa-kinasa 3
D12.776.476.568.200.400 MAP kinasa-kinasa 4 6
D12.776.476.568.200.500 MAP kinasa-kinasa 5 2
D12.776.476.568.200.600 MAP kinasa-kinasa 6
D12.776.476.568.200.700 MAP kinasa-kinasa 7 1
D12.776.476.568.300 protoonkogenní proteiny c-fes
D12.776.476.568.400 tyrosinkinasové receptory 148
D12.776.476.568.500 protoonkogenní proteiny c-abl 7
D12.776.476.568.650 kinasa Syk 11
D12.776.476.568.800 skupina kinas odvozených od src-genu 50
D12.776.476.568.900 protein-tyrosinkináza ZAP-70 21

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