Ribosomal Protein S6 Kinases [kinasy ribozomálního proteinu S6]
- Terms
-
kinasa S6
kinasy ribosomálního proteinu S6
kináza S6
kinázy ribozomálního proteinu S6
ribozomální S6-kinázy
S6 kináza
S6-kináza
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Ribosomal Protein S6 Kinase
S6 Kinase
S6-H4 Kinase
A family of protein serine/threonine kinases which act as intracellular signalling intermediates. Ribosomal protein S6 kinases are activated through phosphorylation in response to a variety of HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Phosphorylation of RIBOSOMAL PROTEIN S6 by enzymes in this class results in increased expression of 5' top MRNAs. Although specific for RIBOSOMAL PROTEIN S6 members of this class of kinases can act on a number of substrates within the cell. The immunosuppressant SIROLIMUS inhibits the activation of ribosomal protein S6 kinases.
- DUI
- D019893 MeSH Browser
- CUI
- M0029535
- Previous indexing
- Protein-Serine-Threonine Kinases (1993-1997); Protein Kinases (1985-1992)
- History note
- 2003(1998); use RIBOSOMAL PROTEIN S6 KINASES (NM) 1985-1997
- Public note
- 2003; see RIBOSOMAL PROTEIN S6 KINASE 1998-2002; RIBOSOMAL PROTEIN S6 KINASE was indexed under PROTEIN-SERINE-THREONINE KINASES 1993-1997 & PROTEIN KINASES 1985-1992
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
RPS6KC1 protein, human Chemical MeSH Browser
Rps6kb1 protein, rat Chemical MeSH Browser