A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN S6 KINASES, 70-KDA by their apparent molecular size and the fact they contain two functional kinase domains. Although considered RIBOSOMAL PROTEIN S6 KINASES, members of this family are activated via the MAP KINASE SIGNALING SYSTEM and have been shown to act on a diverse array of substrates that are involved in cellular regulation such as RIBOSOMAL PROTEIN S6 and CAMP RESPONSE ELEMENT-BINDING PROTEIN.

DUI

D038744 MeSH Prohlížeč

CUI

M0223389

RN

EC 2.7.11.1

Předchozí užití

Protein-Serine-Threonine Kinases (1993-1997); Ribosomal Protein S6 Kinase (1998-2002)

Historická pozn.

2005(2002); for PP90(RSK) & PP90(RSK) use RIBOSOMAL PROTEIN S6 KINASES 1998-2002

Veřejná pozn.

2005; see RIBOSOMAL PROTEIN S6 KINASES, 90KD 2003-2004; MAP-KINASE-ACTIVATED KINASE 1 (now RIBOSOMAL PROTEIN S6 KINASES, 90KDa) was indexed under RIBOSOMAL PROTEIN S6 KINASE 1993-2002; for PP90(RSK) & PP90(RSK) see RIBOSOMAL PROTEIN S6 KINASE 1998-2002