Afatinib [afatinib]
topical
62
- Terms
-
Gilotrif
-
(2E)-N-(4-(3-Chloro-4-fluoroanilino)-7-(((3S)-oxolan-3-yl)oxy)quinoxazolin-6-yl)-4-(dimethylamino)but-2-enamide
Afatinib Dimaleate
Afatinib Maleate
BIBW 2992
BIBW-2992
BIBW-2992-MA2
BIBW-2992MA2
BIBW2992
BIBW2992 MA2
Gilotrif
Persistent link
https://www.medvik.cz/link/D000077716
Definition
A quinazoline and butenamide derivative that acts as a tyrosine kinase inhibitor of epidermal growth factor receptors (ERBB RECEPTORS) and is used in the treatment of metastatic NON-SMALL CELL LUNG CANCER.
- DUI
- D000077716 MeSH Browser
- CUI
- M0561143
- CAS
- 2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-, (2E)-
- History note
- 2019 (2007)
- Public note
- 2019; AFATINIB was indexed under QUINAZOLINES 2007-2018
Allowable subheadings
- AD
- administration & dosage 13
- AE
- adverse effects 4
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology 8
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 16
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records