Alefacept [alefacept]
topical
4
- Terms
-
Amevive
-
Amevive
LFA-3 IgG(1) Fusion Protein
LFA-3 IgG1 Fusion Protein
Persistent link
https://www.medvik.cz/link/D000077944
Definition
A recombinant human fusion protein of LFA-3 antigen and immunoglobulin IGG1 that binds to CD2 ANTIGENS on memory T-LYMPHOCYTES, preventing their activation and proliferation. It is used in the management of moderate to severe chronic plaque PSORIASIS.
- DUI
- D000077944 MeSH Browser
- CUI
- M0374901
- History note
- 2019 (2000)
- Public note
- 2019; ALEFACEPT was indexed under RECOMBINANT FUSION PROTEINS 2000-2018
Allowable subheadings
- AD
- administration & dosage 1
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics 1
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records