Heavy chains of IMMUNOGLOBULIN G having a molecular weight of approximately 51 kDa. They contain about 450 amino acid residues arranged in four domains and an oligosaccharide component covalently bound to the Fc fragment constant region. The gamma heavy chain subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the IMMUNOGLOBULIN G isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than the heavy chains of the other IMMUNOGLOBULIN ISOTYPES.

Anotace

gammopathy: coordinate IMMUNOGLOBULIN GAMMA-CHAINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM) or HEAVY CHAIN DISEASE (IM), follow text; DF: IG GAMMA CHAIN

DUI

D007142 MeSH Prohlížeč

CUI

M0011131

Předchozí užití

Immunoglobulin Fragments (1973-1975); Immunoglobulins, Heavy Chain (1975); IgG (1973-1975)

Historická pozn.

2006 (1976)

Veřejná pozn.

2006; see IMMUNOGLOBULINS, GAMMA-CHAIN 1992-2005, see IMMUNOGLOBULINS, GAMMA CHAIN 1991, see IMMUNOGLOBULINS, HEAVY CHAIN 1976-1990