Duocarmycins [duokarmyciny]

topical
Terms

duokarmycin

 

Duocarmycin

Persistent link   https://www.medvik.cz/link/D000080890
Definition

A group of pyrroloindole compounds often with additional spirocyclic unit(s) and their analogs originally isolated from STREPTOMYCES. They bind DNA minor grooves with adenine-N3 alkylation activity.

DUI
D000080890 MeSH Browser
CUI
M000648583
Previous indexing
Indoles (1988-2019); Pyrroles (1988-2019)
History note
2020
Public note
2020

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine

D Chemicals and Drugs
D03 Heterocyclic Compounds 190
D03.383 Heterocyclic Compounds, 1-Ring 34
D03.383.129 Azoles 87
D03.383.129.578 Pyrroles 381
D03.383.129.578.075 Atorvastatin 145
D03.383.129.578.150 Cromakalim
D03.383.129.578.275 Duocarmycins
D03.383.129.578.399 Maleimides 11
D03.383.129.578.617 Porphobilinogen 11
D03.383.129.578.748 Prodigiosin 3
D03.383.129.578.770 Pyrrolnitrin 1
D03.383.129.578.805 Ryanodine 17
D03.383.129.578.823 Sunitinib 204
D03.383.129.578.840 Tetrapyrroles 10
D03.383.129.578.910 Tolmetin 3
D03.633 Heterocyclic Compounds, Fused-Ring
D03.633.100 Heterocyclic Compounds, 2-Ring 24
D03.633.100.473 Indoles 826
D03.633.100.473.025 Adrenochrome 6
D03.633.100.473.050 Alcian Blue 6
D03.633.100.473.144 Carbazoles 69
D03.633.100.473.231 Cytochalasins 13
D03.633.100.473.250 Delavirdine
D03.633.100.473.278 Duocarmycins
D03.633.100.473.305 Fluvastatin 22
D03.633.100.473.360 Gliotoxin 3
D03.633.100.473.385 Hydroxytryptophol
D03.633.100.473.390 Ibogaine 13
D03.633.100.473.391 Indapamide 214
D03.633.100.473.393 Indican 11
D03.633.100.473.396 Indigo Carmine 4
D03.633.100.473.400 Indocyanine Green 91
D03.633.100.473.402 Indole Alkaloids 9
D03.633.100.473.404 Indoleacetic Acids 188
D03.633.100.473.412 Indolequinones 1
D03.633.100.473.416 Indolosesquiterpenes
D03.633.100.473.420 Indomethacin 362
D03.633.100.473.432 Indoramin
D03.633.100.473.469 Iprindole
D03.633.100.473.525 Isatin 7
D03.633.100.473.615 Methisazone 2
D03.633.100.473.629 Molindone
D03.633.100.473.725 Oxyphenisatin Acetate
D03.633.100.473.746 Panobinostat 5
D03.633.100.473.766 Perindopril 355
D03.633.100.473.808 Skatole 6
D03.633.100.473.840 Sporidesmins
D03.633.100.473.877 Sunitinib 204
D03.633.100.473.896 Tropisetron 1
D03.633.100.473.914 Tryptamines 118
D03.633.100.473.936 Vemurafenib 67
D03.633.100.473.957 Vilazodone Hydrochloride 2

CC 1065 Chemical MeSH Browser

CC-1065-(N(3)-adenine)-DNA Chemical MeSH Browser

DU 86 Chemical MeSH Browser

KW 2189 Chemical MeSH Browser

N-acetyl-duocarmycin Chemical MeSH Browser

U 76073 Chemical MeSH Browser

U 76074 Chemical MeSH Browser

adozelesin Chemical MeSH Browser

bizelesin Chemical MeSH Browser

carzelesin Chemical MeSH Browser

duocarmycin A Chemical MeSH Browser

duocarmycin B1 Chemical MeSH Browser

duocarmycin B2 Chemical MeSH Browser

duocarmycin SA Chemical MeSH Browser

pyrindamycin A Chemical MeSH Browser

pyrindamycin B Chemical MeSH Browser

yatakemycin Chemical MeSH Browser

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