Ryanodine [ryanodin]
topical
17
Persistent link
https://www.medvik.cz/link/D012433
Definition
A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
- DUI
- D012433 MeSH Browser
- CUI
- M0019318
- CAS
- Ryanodol, 3-(1H-pyrrole-2-carboxylate)
- Previous indexing
- Alkaloids (1970-1974)
- History note
- 91(75); was see under ALKALOIDS 1975-90
- Public note
- 91; was see under ALKALOIDS 1975-90
Allowable subheadings
- AD
- administration & dosage 5
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics 1
- PD
- pharmacology 7
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 1
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D02.455.849.291.184
Diterpene Alkaloids
D02.455.849.291.564
Pleuromutilins
D03.132.032
Acridones
D03.132.285
Dihydro-beta-Erythroidine
D03.132.301
Diterpene Alkaloids
D03.132.795
Stemona Alkaloids
D03.383.129.578.150
Cromakalim
D03.383.129.578.275
Duocarmycins