Pleuromutilins [pleuromutiliny]

topical
Terms

drosofilin B
pleuromutilin
pleuromutilinová antibiotika

 

Drosophilin B
Octahydro-5,8-dihydroxy-4,6,9,10- tetramethyl-6-vinyl-3a,9-propano-3aH-cyclopenta- cycloocten-1(4H)-one 8-glycolate
Pleuromutilin
Pleuromutilin Antibiotics

Definition

A tricyclic diterpene natural product isolated from Pleurotus mutilus (now referred to as Clitopilus scyphoides). Possesses modest antibacterial activity against primarily gram-positive bacterial organisms.

DUI
D000097567 MeSH Browser
CUI
M000764155
History note
2024 (1973)
Public note
2024: PLEUROMUTILIN was indexed under DITERPENES and POLYCYCLIC COMPOUNDS 1975-2023, and under CYCLOPARAFFINS and GLYCOLATES 1973-1975

D Chemicals and Drugs
D02.455 Hydrocarbons 139
D02.455.849 Terpenes 139
D02.455.849.291 Diterpenes 51
D02.455.849.291.040 Abietanes 7
D02.455.849.291.075 Aphidicolin 2
D02.455.849.291.162 Atractyloside 2
D02.455.849.291.184 Diterpene Alkaloids
D02.455.849.291.300 Colforsin 23
D02.455.849.291.325 Diterpenes, Clerodane 4
D02.455.849.291.350 Diterpenes, Kaurane 10
D02.455.849.291.400 Ginkgolides 9
D02.455.849.291.500 Phorbols 12
D02.455.849.291.515 Phytanic Acid 1
D02.455.849.291.523 Phytol 1
D02.455.849.291.564 Pleuromutilins
D02.455.849.291.605 Retinaldehyde 5
D02.455.849.291.686 Ryanodine 17
D02.455.849.291.850 Taxoids 389
D02.455.849.291.925 Vitamin A 406
D10 Lipids 2 528