Promyelocytic Leukemia Nuclear Bodies [promyelocytická leukemická tělíska]

topical
Terms

jaderná doména 10
jaderná tělíska PML
ND 10
PML onkogenní doména
PML tělíska
PODs
promyelocytární leukemické tělísko
tělíska PML

 

PML Bodies
PML NBs
PML Nuclear Bodies
Promyelocytic Leukemia Nuclear Body
Promyelocytic Leukemia Protein Bodies
Promyelocytic Leukemia Protein Body

Definition

Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes.

DUI
D000088182 MeSH Browser
CUI
M000740236
Previous indexing
Intranuclear Inclusion Bodies (2008-2021); Promyelocytic Leukemia Protein (2008-2021)
History note
2022
Public note
2022

A Anatomy
A10 Tissues 372
A11 Cells 976
A11.284.430 Intracellular Space 84
A11.284.430.106 Cell Nucleus 809
A11.284.430.106.279 Cell Nucleus Structures 30
A11.284.430.106.279.345 Intranuclear Space 3
A11.284.430.106.279.345.574 Nuclear Bodies
A11.284.430.106.279.345.574.500 Coiled Bodies 11
A11.284.430.106.279.345.574.750 Gemini of Coiled Bodies 1
A11.284.430.106.279.345.574.813 Nuclear Speckles 1
A11.284.430.106.279.345.574.844 Paraspeckles 1
A11.284.430.106.279.345.574.875 Promyelocytic Leukemia Nuclear Bodies