Affinity Labels [afinitní značky]
- Terms
-
afinita - označení
činidla afinitního značení
reagencia afinitní značky
-
Affinity Labeling Reagents
Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.
- Annotation
- D25-26 qualif; use with caution: few apply
- DUI
- D000345 MeSH Browser
- CUI
- M0000530
- Previous indexing
- Binding Sites (1968-1974); Indicators and Reagents (1968-1974)
- History note
- 75
- Public note
- 75
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- CS
- chemical synthesis 3
- CH
- chemistry 4
- CL
- classification
- EC
- economics
- HI
- history
- IP
- isolation & purification
- ME
- metabolism 2
- PK
- pharmacokinetics
- PD
- pharmacology 1
- PO
- poisoning
- RE
- radiation effects 1
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity