Cyclin-Dependent Kinase 8 [cyklin-dependentní kinasa 8]

topical
1
Terms

cyklin-dependentní kináza 8
proteinkinasa Cdk8
proteinkináza Cdk8

 

Cdk8 Cyclin-Dependent Kinase
Cdk8 Protein Kinase
Cell Division Protein Kinase 8

Persistent link   https://www.medvik.cz/link/D056850
Definition

A CYCLIN C dependent kinase that is an important component of the mediator complex. The enzyme is activated by its interaction with CYCLIN C and plays a role in transcriptional regulation by phosphorylating RNA POLYMERASE II.

DUI
D056850 MeSH Browser
CUI
M0529506
Previous indexing
Cyclin-Dependent Kinases (1995-2009)
History note
2010
Public note
2010

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 1
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 1
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D05 Macromolecular Substances 103
D05.500 Multiprotein Complexes 65
D05.500.374 Mediator Complex 5
D05.500.374.249 Cyclin C 1
D05.500.374.500 Cyclin-Dependent Kinase 8 1
D05.500.374.750 Mediator Complex Subunit 1 1
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 547
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.620 Phosphotransferases (Alcohol Group Acceptor) 32
D08.811.913.696.620.682 Protein Kinases 248
D08.811.913.696.620.682.700 Protein Serine-Threonine Kinases 271
D08.811.913.696.620.682.700.646 Proline-Directed Protein Kinases 1
D08.811.913.696.620.682.700.646.500 Cyclin-Dependent Kinases 228
D08.811.913.696.620.682.700.646.500.500 CDC2-CDC28 Kinases 25
D08.811.913.696.620.682.700.646.500.750 Cyclin-Dependent Kinase 2 58
D08.811.913.696.620.682.700.646.500.812 Cyclin-Dependent Kinase 3
D08.811.913.696.620.682.700.646.500.875 Cyclin-Dependent Kinase 4 79
D08.811.913.696.620.682.700.646.500.937 Cyclin-Dependent Kinase 6 66
D08.811.913.696.620.682.700.646.500.968 Cyclin-Dependent Kinase 8 1
D08.811.913.696.620.682.700.646.500.984 Maturation-Promoting Factor 14
D08.811.913.696.620.682.700.646.500.992 Cyclin-Dependent Kinase-Activating Kinase 2
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 577
D12.776.157 Carrier Proteins 546
D12.776.157.057 Adaptor Proteins, Signal Transducing 176
D12.776.157.057.072 Mediator Complex 5
D12.776.157.057.072.249 Cyclin C 1
D12.776.157.057.072.500 Cyclin-Dependent Kinase 8 1
D12.776.157.057.072.750 Mediator Complex Subunit 1 1
D12.776.167 Cell Cycle Proteins 328
D12.776.167.200 Cyclin-Dependent Kinases 228
D12.776.167.200.067 CDC2-CDC28 Kinases 25
D12.776.167.200.323 Cyclin-Dependent Kinase 2 58
D12.776.167.200.387 Cyclin-Dependent Kinase 3
D12.776.167.200.451 Cyclin-Dependent Kinase 4 79
D12.776.167.200.515 Cyclin-Dependent Kinase 6 66
D12.776.167.200.548 Cyclin-Dependent Kinase 8 1
D12.776.167.200.580 Maturation-Promoting Factor 14
D12.776.167.200.790 Cyclin-Dependent Kinase-Activating Kinase 2
D12.776.476 Intracellular Signaling Peptides and Proteins 174
D12.776.476.024 Adaptor Proteins, Signal Transducing 176
D12.776.476.024.388 Mediator Complex 5
D12.776.476.024.388.249 Cyclin C 1
D12.776.476.024.388.500 Cyclin-Dependent Kinase 8 1
D12.776.476.024.388.750 Mediator Complex Subunit 1 1
D12.776.476.563 Protein Serine-Threonine Kinases 271
D12.776.476.563.646 Proline-Directed Protein Kinases 1
D12.776.476.563.646.500 Cyclin-Dependent Kinases 228
D12.776.476.563.646.500.500 CDC2-CDC28 Kinases 25
D12.776.476.563.646.500.750 Cyclin-Dependent Kinase 2 58
D12.776.476.563.646.500.812 Cyclin-Dependent Kinase 3
D12.776.476.563.646.500.875 Cyclin-Dependent Kinase 4 79
D12.776.476.563.646.500.937 Cyclin-Dependent Kinase 6 66
D12.776.476.563.646.500.968 Cyclin-Dependent Kinase 8 1
D12.776.476.563.646.500.984 Maturation-Promoting Factor 14
D12.776.476.563.646.500.992 Cyclin-Dependent Kinase-Activating Kinase 2
D12.776.660 Nuclear Proteins 452
D12.776.660.551 Mediator Complex 5
D12.776.660.551.249 Cyclin C 1
D12.776.660.551.500 Cyclin-Dependent Kinase 8 1
D12.776.660.551.750 Mediator Complex Subunit 1 1

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