Cyclin-Dependent Kinase 2 [cyklin-dependentní kinasa 2]

topical
58
Terms

cyklin-dependentní kináza 2
kinasa p33cdk2
kináza p33cdk2
protein CDK2
proteinkinasa Cdk2
proteinkináza Cdk2

 

Cdc2-Related Protein Kinase
CDK2 Protein
Cdk2 Protein Kinase
p33cdk2 Kinase

Persistent link   https://www.medvik.cz/link/D051357
Definition

A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.

DUI
D051357 MeSH Browser
CUI
M0191671
RN
EC 2.7.11.22
History note
2006(1991)
Public note
2006; CYCLIN-DEPENDENT KINASE 2 was indexed under CDC2-CDC28 KINASES 2004-2005, & under CYCLIN-DEPENDENT KINASES 1991-2003, & under PROTEIN KINASES 1991-1994

D Chemicals and Drugs
D08.811 Enzymes 1 547
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.620.682 Protein Kinases 247
D08.811.913.696.620.682.700 Protein Serine-Threonine Kinases 271
D08.811.913.696.620.682.700.646 Proline-Directed Protein Kinases 1
D08.811.913.696.620.682.700.646.500 Cyclin-Dependent Kinases 227
D08.811.913.696.620.682.700.646.500.500 CDC2-CDC28 Kinases 25
D08.811.913.696.620.682.700.646.500.750 Cyclin-Dependent Kinase 2 58
D08.811.913.696.620.682.700.646.500.812 Cyclin-Dependent Kinase 3
D08.811.913.696.620.682.700.646.500.875 Cyclin-Dependent Kinase 4 79
D08.811.913.696.620.682.700.646.500.937 Cyclin-Dependent Kinase 6 66
D08.811.913.696.620.682.700.646.500.968 Cyclin-Dependent Kinase 8 1
D08.811.913.696.620.682.700.646.500.984 Maturation-Promoting Factor 14
D08.811.913.696.620.682.700.646.500.992 Cyclin-Dependent Kinase-Activating Kinase 2
D12.776 Proteins 2 575
D12.776.167 Cell Cycle Proteins 327
D12.776.167.200 Cyclin-Dependent Kinases 227
D12.776.167.200.067 CDC2-CDC28 Kinases 25
D12.776.167.200.323 Cyclin-Dependent Kinase 2 58
D12.776.167.200.387 Cyclin-Dependent Kinase 3
D12.776.167.200.451 Cyclin-Dependent Kinase 4 79
D12.776.167.200.515 Cyclin-Dependent Kinase 6 66
D12.776.167.200.548 Cyclin-Dependent Kinase 8 1
D12.776.167.200.580 Maturation-Promoting Factor 14
D12.776.476.563.646.500 Cyclin-Dependent Kinases 227
D12.776.476.563.646.500.500 CDC2-CDC28 Kinases 25
D12.776.476.563.646.500.750 Cyclin-Dependent Kinase 2 58
D12.776.476.563.646.500.812 Cyclin-Dependent Kinase 3
D12.776.476.563.646.500.875 Cyclin-Dependent Kinase 4 79
D12.776.476.563.646.500.937 Cyclin-Dependent Kinase 6 66
D12.776.476.563.646.500.968 Cyclin-Dependent Kinase 8 1
D12.776.476.563.646.500.984 Maturation-Promoting Factor 14
D12.776.476.563.646.500.992 Cyclin-Dependent Kinase-Activating Kinase 2