Maturation-Promoting Factor [faktor podporující zrání]

topical
14
Terms

faktor podporující M fázi
faktor podporující mitózu

 

Histone H1 Kinase, Growth-Associated
Histone H1 Kinase, M-Phase-Specific
M Phase-Promoting Factor
Mitosis-Promoting Factor

Persistent link   https://www.medvik.cz/link/D016200
Definition

Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.

DUI
D016200 MeSH Browser
CUI
M0024733
Previous indexing
Growth Substances (1979-1990)
History note
91; HISTONE H1 KINASE, M-PHASE-SPECIFIC was HISTONE H1 KINASE, M PHASE-SPECIFIC 1991-93
Public note
91; HISTONE H1 KINASE, M-PHASE-SPECIFIC was HISTONE H1 KINASE, M PHASE-SPECIFIC 1991-93

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects 1
EC
economics
GE
genetics 1
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 7
PK
pharmacokinetics
PD
pharmacology 1
PH
physiology 1
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 547
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.620 Phosphotransferases (Alcohol Group Acceptor) 32
D08.811.913.696.620.682 Protein Kinases 248
D08.811.913.696.620.682.700 Protein Serine-Threonine Kinases 271
D08.811.913.696.620.682.700.646 Proline-Directed Protein Kinases 1
D08.811.913.696.620.682.700.646.500 Cyclin-Dependent Kinases 228
D08.811.913.696.620.682.700.646.500.500 CDC2-CDC28 Kinases 25
D08.811.913.696.620.682.700.646.500.750 Cyclin-Dependent Kinase 2 58
D08.811.913.696.620.682.700.646.500.812 Cyclin-Dependent Kinase 3
D08.811.913.696.620.682.700.646.500.875 Cyclin-Dependent Kinase 4 79
D08.811.913.696.620.682.700.646.500.937 Cyclin-Dependent Kinase 6 66
D08.811.913.696.620.682.700.646.500.968 Cyclin-Dependent Kinase 8 1
D08.811.913.696.620.682.700.646.500.984 Maturation-Promoting Factor 14
D08.811.913.696.620.682.700.646.500.984.500 CDC2 Protein Kinase 36
D08.811.913.696.620.682.700.646.500.992 Cyclin-Dependent Kinase-Activating Kinase 2
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 577
D12.776.167 Cell Cycle Proteins 328
D12.776.167.200 Cyclin-Dependent Kinases 228
D12.776.167.200.067 CDC2-CDC28 Kinases 25
D12.776.167.200.323 Cyclin-Dependent Kinase 2 58
D12.776.167.200.387 Cyclin-Dependent Kinase 3
D12.776.167.200.451 Cyclin-Dependent Kinase 4 79
D12.776.167.200.515 Cyclin-Dependent Kinase 6 66
D12.776.167.200.548 Cyclin-Dependent Kinase 8 1
D12.776.167.200.580 Maturation-Promoting Factor 14
D12.776.167.200.580.500 CDC2 Protein Kinase 36
D12.776.167.200.790 Cyclin-Dependent Kinase-Activating Kinase 2
D12.776.476 Intracellular Signaling Peptides and Proteins 174
D12.776.476.563 Protein Serine-Threonine Kinases 271
D12.776.476.563.646 Proline-Directed Protein Kinases 1
D12.776.476.563.646.500 Cyclin-Dependent Kinases 228
D12.776.476.563.646.500.500 CDC2-CDC28 Kinases 25
D12.776.476.563.646.500.750 Cyclin-Dependent Kinase 2 58
D12.776.476.563.646.500.812 Cyclin-Dependent Kinase 3
D12.776.476.563.646.500.875 Cyclin-Dependent Kinase 4 79
D12.776.476.563.646.500.937 Cyclin-Dependent Kinase 6 66
D12.776.476.563.646.500.968 Cyclin-Dependent Kinase 8 1
D12.776.476.563.646.500.984 Maturation-Promoting Factor 14
D12.776.476.563.646.500.984.500 CDC2 Protein Kinase 36
D12.776.476.563.646.500.992 Cyclin-Dependent Kinase-Activating Kinase 2

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