Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant toxins, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect.

Annotation

coordinate IM with specific toxin (IM) + specific immune substance (NIM)

DUI

D000922 MeSH Browser

CUI

M0001373

Previous indexing

Antibodies, Monoclonal (1982-1986); Antigens, Surface (1979-1986); Antitoxins (1966-1986); Cytotoxicity, Immunologic (1978-1986); Ricin (1978-1985)

History note

90; was ANTIBODY-TOXIN CONJUGATES 1987-89

Online note

use IMMUNOTOXINS to search ANTIBODY-TOXIN CONJUGATES 1987-89

Public note

90; was ANTIBODY-TOXIN CONJUGATES 1987-89