Apolipoproteins E [apolipoproteiny E]
- Terms
-
Apo E
ApoE
apoprotein E
apoproteiny E
isoproteiny ApoE
izoproteiny ApoE
-
Apo E
Apo E Isoproteins
Apo-E
ApoE
Apolipoprotein E Isoproteins
Apoprotein (E)
Apoproteins E
A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.
- DUI
- D001057 MeSH Browser
- CUI
- M0001601
- Previous indexing
- Apolipoproteins (1977-1984)
- History note
- 1985; for APOLIPOPROTEIN E ISOPROTEINS use APOLIPOPROTEINS E 1985-2006 & use APOLIPOPROTEINS 1983-1984
- Public note
- 1985; APOLIPOPROTEIN E ISOPROTEINS was indexed under APOLIPOPROTEINS E 1985-2006 & under APOLIPOPROTEINS 1983-1984
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects 5
- AG
- agonists
- AN
- analysis 19
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 2
- BL
- blood 14
- CF
- cerebrospinal fluid 1
- CS
- chemical synthesis
- CH
- chemistry 5
- CL
- classification 3
- DF
- deficiency 17
- DE
- drug effects
- EC
- economics
- GE
- genetics 116
- HI
- history
- IM
- immunology
- IP
- isolation & purification 1
- ME
- metabolism 26
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 12
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
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