beta 2-Microglobulin [beta-2-mikroglobulin]
- Terms
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beta 2-mikroglobulin
beta2M
-
Thymotaxin
An 11-kDa protein associated with the outer membrane of many cells including LYMPHOCYTES. It is the small subunit of MHC CLASS I MOLECULES. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, CEREBROSPINAL FLUID, and urine of healthy individuals, and to a much greater degree in the urine and plasma of patients with tubular PROTEINURIA, renal failure, or kidney transplants.
- DUI
- D001613 MeSH Browser
- CUI
- M0002412
- Previous indexing
- Beta Globulins (1973-1974)
- History note
- 1991 (1975); use BETA 2 MICROGLOBULIN 1984-1990
- Public note
- 1991; see BETA 2 MICROGLOBULIN 1984-1990; BETA 2-MICROGLOBULIN was indexed under BETA GLOBULINS 1975-1983
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis 10
- AI
- antagonists & inhibitors
- BI
- biosynthesis 2
- BL
- blood 29
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 2
- CL
- classification
- DF
- deficiency 1
- DE
- drug effects 1
- EC
- economics
- GE
- genetics 7
- HI
- history
- IM
- immunology 5
- IP
- isolation & purification
- ME
- metabolism 10
- PK
- pharmacokinetics
- PD
- pharmacology 1
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine 6
B2M protein, human Chemical MeSH Browser
beta 2-microglobulin, des-lysyl(58)- Chemical MeSH Browser