A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.

DUI

D002051 MeSH Browser

CUI

M0003058

History note

1998 (1968)

Public note

1998; see BURKITT'S LYMPHOMA 1968-1997; for LEUKEMIA, B-CELL, ACUTE & BURKITT LEUKEMIA see LEUKEMIA, B-CELL, ACUTE 1989-2007; for BURKITT TUMOR see BURKITT'S TUMOR 1968-1997; for LYMPHOMA, BURKITT see LYMPHOMA, BURKITT'S 1968-1997