Busulfan [busulfan]
- Terms
-
Busulfex
Mylecytan
Myleran
n-butan-1,3-di(methylsulfonát)
-
Busulfan Wellcome
Busulfex
Busulphan
Glyzophrol
Myelosan
Mylecytan
Myleran
Myléran
n-Butane-1,3-di(methylsulfonate)
An alkylating agent having a selective immunosuppressive effect on BONE MARROW. It has been used in the palliative treatment of chronic myeloid leukemia (MYELOID LEUKEMIA, CHRONIC), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
- DUI
- D002066 MeSH Browser
- CUI
- M0003079
- CAS
- 1,4-Butanediol, dimethanesulfonate
Allowable subheadings
- AD
- administration & dosage 24
- AE
- adverse effects 14
- AG
- agonists
- AA
- analogs & derivatives 8
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics 6
- PD
- pharmacology 8
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 18
- TO
- toxicity 2
- UR
- urine