Caffeine [kofein]
- Terms
-
Peyona
-
1,3,7-Trimethylxanthine
Caffedrine
Coffeinum N
Coffeinum Purrum
Dexitac
Durvitan
No Doz
Percoffedrinol N
Percutaféine
Quick-Pep
Vivarin
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
- DUI
- D002110 MeSH Browser
- CUI
- M0003138
- CAS
- 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-
Allowable subheadings
- AD
- administration & dosage 72
- AE
- adverse effects 62
- AG
- agonists 2
- AA
- analogs & derivatives 4
- AN
- analysis 30
- AI
- antagonists & inhibitors
- BI
- biosynthesis 1
- BL
- blood 2
- CF
- cerebrospinal fluid
- CS
- chemical synthesis 1
- CH
- chemistry 16
- CL
- classification
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology 2
- IP
- isolation & purification 9
- ME
- metabolism 35
- PK
- pharmacokinetics 19
- PD
- pharmacology 96
- PO
- poisoning 3
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 53
- TO
- toxicity 12
- UR
- urine 4
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