A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.

DUI

D002216 MeSH Browser

CUI

M0003319

CAS

L-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-, (S)-

Previous indexing

Kininase II/antagonists & inhibitors (1973-1979); Peptide Peptidohydrolases (1966-1967) /antagonists & inhibitors (1968-1972); Proline (1966-1974) /antagonists & inhibitors (1975-1979)

History note

86(80); was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93

Online note

use CAPTOPRIL to search SQ 14225 1980-93

Public note

86; was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93