Captopril [kaptopril]
topical
184
- Terms
-
(S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
Capoten
Lopirin
SQ-14,225
SQ-14,534
SQ-14225
SQ-14534
Persistent link
https://www.medvik.cz/link/D002216
Definition
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
- DUI
- D002216 MeSH Browser
- CUI
- M0003319
- CAS
- L-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-, (S)-
- Previous indexing
- Kininase II/antagonists & inhibitors (1973-1979); Peptide Peptidohydrolases (1966-1967) /antagonists & inhibitors (1968-1972); Proline (1966-1974) /antagonists & inhibitors (1975-1979)
- History note
- 86(80); was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93
- Online note
- use CAPTOPRIL to search SQ 14225 1980-93
- Public note
- 86; was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93
Allowable subheadings
- AD
- administration & dosage 49
- AE
- adverse effects 12
- AG
- agonists 0
- AA
- analogs & derivatives 3
- AN
- analysis 1
- AI
- antagonists & inhibitors 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 3
- CL
- classification 0
- EC
- economics 0
- HI
- history 1
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 4
- PK
- pharmacokinetics 7
- PD
- pharmacology 68
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 81
- TO
- toxicity 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs