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cefalosporiny [Cephalosporins]

tematický

573

Termíny: antibiotika cefalosporinová
cefalosporanová kyselina
cefalosporanové kyseliny
cefalosporin
cefalosporinová antibiotika
deriváty kyseliny cefalosporanové

: Antibiotics, Cephalosporin
Cephalosporanic Acid
Cephalosporanic Acids
Cephalosporin
Cephalosporin Antibiotic

Perzistentní odkaz https://www.medvik.cz/link/D002511

Definice

Skupina širokospektrých beta-laktamových antibiotik, jejichž název je odvozen z plísně Cephalosporium acremonium, z níž byly tyto látky poprvé izolovány. Jejich strukturním základem je betalaktamový kruh, z chem. hlediska jsou to deriváty kyseliny 7-aminocefalosporanové a mohou být jak přírodní, tak i semisyntetická. Tyto látky znemožňují syntézu peptidoglykanové buněčné stěny bakterií. Působí baktericidně, a to na poměrně široké rozpětí různých bakterií. Neúčinkují však na enterokoky. Dělí se běžně do pěti tříd, I., II., III., IV. a V. generace cefalosporinů. (upraveno podle Wikipedie 2022 http://www.cs.wikipedia.org/)

A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.

DUI: D002511 MeSH Prohlížeč
CUI: M0003827
Historická pozn.: 66(65)
Veřejná pozn.: 66

Povolená podhesla

AG: agonisté
AN: analýza 11
AI: antagonisté a inhibitory 2
AD: aplikace a dávkování 136
BI: biosyntéza 6
CS: chemická syntéza 3
CH: chemie 18
HI: dějiny 2
EC: ekonomika 5
PK: farmakokinetika 28
PD: farmakologie 98
IM: imunologie 1
IP: izolace a purifikace 2
CL: klasifikace 15
BL: krev 6
ME: metabolismus 13
UR: moč 2
CF: mozkomíšní mok
ST: normy 1
PO: otrava 1
AE: škodlivé účinky 46
TU: terapeutické užití 249
TO: toxicita 1
RE: účinky záření
SD: zásobování a distribuce

... Výskyt v záznamech Medvik

D Chemikálie a léčiva

D02 organické látky 391

D02.065 amidy 260

D02.065.589 laktamy 143

D02.065.589.099 beta-laktamy 74

D02.065.589.099.124 karbapenemy 118

D02.065.589.099.249 cefalosporiny 573

D02.065.589.099.249.150 cefamandol 7

D02.065.589.099.249.160 cefazolin 16

D02.065.589.099.249.169 cefdinir

D02.065.589.099.249.173 cefepim 4

D02.065.589.099.249.175 cefiderokol 3

D02.065.589.099.249.176 cefpodoxim

D02.065.589.099.249.177 cefonicid 2

D02.065.589.099.249.179 cefozopran

D02.065.589.099.249.181 cefpirom

D02.065.589.099.249.183 cefprozil

D02.065.589.099.249.185 cefsulodin 1

D02.065.589.099.249.186 ceftarolin

D02.065.589.099.249.187 ceftibuten 2

D02.065.589.099.249.188 cefuroxim 51

D02.065.589.099.249.190 cefacetril

D02.065.589.099.249.200 cefalexin 13

D02.065.589.099.249.210 cefaloridin 14

D02.065.589.099.249.250 cefamyciny 1

D02.065.589.099.374 kyseliny klavulanové 18

D02.065.589.099.500 monobaktamy 6

D02.065.589.099.625 moxalaktam

D02.065.589.099.750 peniciliny 737

D02.886 sloučeniny síry 42

D02.886.665 thiaziny 53

D02.886.665.074 cefalosporiny 573

D02.886.665.074.150 cefamandol 7

D02.886.665.074.160 cefazolin 16

D02.886.665.074.169 cefdinir

D02.886.665.074.173 cefepim 4

D02.886.665.074.175 cefiderokol 3

D02.886.665.074.176 cefpodoxim

D02.886.665.074.177 cefonicid 2

D02.886.665.074.179 cefozopran

D02.886.665.074.181 cefpirom

D02.886.665.074.183 cefprozil

D02.886.665.074.185 cefsulodin 1

D02.886.665.074.186 ceftarolin

D02.886.665.074.187 ceftibuten 2

D02.886.665.074.188 cefuroxim 51

D02.886.665.074.190 cefacetril

D02.886.665.074.200 cefalexin 13

D02.886.665.074.210 cefaloridin 14

D02.886.665.074.250 cefamyciny 1

D02.886.665.150 chlormezanon 4

D02.886.665.275 meloxikam 15

D02.886.665.400 nifurtimox

D02.886.665.500 piroxikam 55

D02.886.665.785 thiadiaziny 13

D02.886.665.985 xylazin 12

D03 heterocyklické sloučeniny 190

D03.633 heterocyklické sloučeniny se spojenými kruhy

D03.633.100 heterocyklické sloučeniny bicyklické 24

D03.633.100.300 beta-laktamy 74

D03.633.100.300.124 karbapenemy 118

D03.633.100.300.249 cefalosporiny 573

D03.633.100.300.249.150 cefamandol 7

D03.633.100.300.249.160 cefazolin 16

D03.633.100.300.249.169 cefdinir

D03.633.100.300.249.173 cefepim 4

D03.633.100.300.249.175 cefiderokol 3

D03.633.100.300.249.176 cefpodoxim

D03.633.100.300.249.177 cefonicid 2

D03.633.100.300.249.179 cefozopran

D03.633.100.300.249.181 cefpirom

D03.633.100.300.249.183 cefprozil

D03.633.100.300.249.185 cefsulodin 1

D03.633.100.300.249.186 ceftarolin

D03.633.100.300.249.187 ceftibuten 2

D03.633.100.300.249.188 cefuroxim 51

D03.633.100.300.249.190 cefacetril

D03.633.100.300.249.200 cefalexin 13

D03.633.100.300.249.210 cefaloridin 14

D03.633.100.300.249.250 cefamyciny 1

D03.633.100.300.374 kyseliny klavulanové 18

D03.633.100.300.500 monobaktamy 6

D03.633.100.300.625 moxalaktam

D03.633.100.300.750 peniciliny 737

((1-methyl)ethoxycarbonyloxy)-ethyl 7-(2-(2-amino-4-thiazole)-2-methoxyaminoacetamido)-3-(2-propenyl)-3-cephem-4-carboxylate Chemical MeSH Prohlížeč

(5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl 7-(2-(2-amino-4-thiazole)-2-methoxyiminoacetamido)-3-(2-propenyl)-3-cephem-4-carboxylate Chemical MeSH Prohlížeč

1-dethia-3-aza-1-carba-2-oxacephem Chemical MeSH Prohlížeč

16-hydroxyadipoyl-7-aminodeacetoxycephalosporanic acid Chemical MeSH Prohlížeč

2,3-di-exo-methylencepham Chemical MeSH Prohlížeč

3-((3-(1-acetoxyethyl)isoxazol-5-yl)ethenyl)-7-((2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)cephalosporanic acid Chemical MeSH Prohlížeč

3-((4-nitrophenoxy)methyl)-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid 5,5-dioxide Chemical MeSH Prohlížeč

3-(2-(2-aminothiazol-4-yl)-2-((((5-cyano-3,4-dihydroxythiophen-2-yl)carboxymethyl)oxy)imino)acetamido)-7-(3-(1-quinolinium)-1-propenyl)-5-thia-1-azabicyclo(4.2.0)octane-2-carboxylic acid Chemical MeSH Prohlížeč

3-chloro-1-carbacephem Chemical MeSH Prohlížeč

3-chlorophenylacetamidocephalosporanic acid Chemical MeSH Prohlížeč

3-dansylamidomethyl-7-beta(thienyl-2')-acetamidoceph-3-em-4-oate Chemical MeSH Prohlížeč

3-ethynylcephalosporin Chemical MeSH Prohlížeč

7 beta-(2-carboxy-2-(4-hydroxyphenyl)acetamido)-7 alpha-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-1-oxa-1-dethia-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7 beta-(5-aminoadipamido)-3 beta-hydroxy-3 alpha-methylcepham-4 alpha-carboxylic acid Chemical MeSH Prohlížeč

7 beta-(5-hydroxy-5-carboxyvarelamido)-3-hydroxymethyl-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-((2-aminothiazol--4-yl)methoximinoacetylamino)-1-carba(1-dethia)-3-(2-aminothiazol-4-yl)-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-((2-aminothiazol-4-yl)-2-(N-hydroxyimino)acetamido)-3-((3-methoxyisoxazol-5-yl)ethenyl)cephalosporanic acid Chemical MeSH Prohlížeč

7-((2-aminothiazol-4-yl)-2--(N-hydroxyimino)acetamido)-3-((3-chloroisoxazol-5-yl)ethenyl)cyclosporanic acid Chemical MeSH Prohlížeč

7-((2-aminothiazol-4-yl)-4--methoximinoacetylamino)-1-carba(1-dethia)-3-(2-(5-nitrothiazol-2-yl)thiazol-4-yl)-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-((2-aminothiazol-4-yl)-methoximinoacetylamino)-1-carba(1-dethia)-3-(2-((phenyl)(2-pyridyl)methyl)thiazol-4-yl)-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-((2-aminothiazol-4-yl)methoximinoacetylamino)-1-carba(1-dethia)-3-(2-phenylthiazol-4-yl)-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-((3-(2-furoyl)ureido)phenylacetamido)cephalosporanic acid Chemical MeSH Prohlížeč

7-(-2-(2-aminothiazol-4-yl)-2-(3-(3-hydroxy-4-pyridon-1-yl)-3-carboxypropoxyimino)acetamido)-3-(1,2,3-thiadiazol-5-yl)-thiomethyl-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-(1-pentafluorophenoxyacetamido)-3-(2-(5-methyl-1,3,4-thiodiazolyl)thiomethyl)-delta(3)-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-(2- (2-aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxyimino)acetamido)-3-(3,4-dihydroxybenzoyloxy)methyl-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-(2-(2-amino-4-thiazolyl)--4-carboxy-2-butenoylamino)-3-vinyl-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-(2-(2-amino-5-chlorothiazol-4-yl)-2-methoxyiminoacetamido)-3-(imidazo(1,5-a)-pyridinium-1-yl)methyl-3-cephem-4-carboxylate Chemical MeSH Prohlížeč

7-(2-(2-amino-5-chlorothiazole-4-yl)-2-methoxyiminoacetamido)-3-azolium-3-cephem-4-carboxylate Chemical MeSH Prohlížeč

7-(2-(2-aminothiazol-4-yl)- 2-(1-carboxyl-1-methylethoxyimino)acetamido)-3-(3-(3,4-dihydroxybenzoyloxy)-1-propen-1-yl)-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-(2-(2-aminothiazol-4-yl)-2- (1-carboxy-1-methylethoxyimino)acetamido)-3-(3-(5,6-dihydroxybenzimidazol-1-yl)propen-1-yl)-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-(2-(2-aminothiazol-4-yl)-2-(((1,5-dihydroxy-4-pyridon-2-yl)methoxy)imino)acetamido)-3-((((4-methyl-5-carboxymethyl)thiazol-2-yl)thio)methyl)-8-oxo-1-aza-4-thiabicyclo(4.2.0)oct-ene-2-carboxylic acid Chemical MeSH Prohlížeč

7-(2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxyimino)acetamido)-3-(3-(2,6-dihydro-7-hydroxy-6-oxoisoquinolin-2-yl)propen-1-yl)-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-(2-(2-aminothiazole-4-yl)-2-(1-carboxy-1-methyl)ethoxyiminoacetamido)-3-(3-hydroxy-4-pyridon-1-yl)methyl-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-(2-(2-aminothiazole-4-yl)-2-methoxyiminoacetamido)-3-(imidazo(1,5-a)pyridinium-2-yl)methyl-3-cephem-4-carboxylate Chemical MeSH Prohlížeč

7-(2-(2-aminothiazolyl)-2-methoxyiminoacetamido)-3-(imidazo(1,2-a)pyridinium-1-yl)methyl-3-cephem-4-carboxylate Chemical MeSH Prohlížeč

7-(2-(5-amino-1,2,4-thiadiazol--3-yl)-2-cyclopentyloxyiminoacetamido)-3-(3,6-diaminoimidazo(1,2-b)pyridazinium-1-yl)methyl-3-cephem-4-carboxylate Chemical MeSH Prohlížeč

7-(2-(5-amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetamido)-3-(1-(3-methylaminopropyl)-1H-imidazo(4,5-b)pyridinium-4-yl)methyl-3-cephem-4-carboxylate Chemical MeSH Prohlížeč

7-(2-(N(b)-2-nitrobenzyloxycarbonyl)hydrazino-3-phenylpropanamido)cephalosporanic acid Chemical MeSH Prohlížeč

7-(2-amino-2-phenylacetamido)-3-(1H-1,2,3-triazol-4-yl)methylthiomethyl-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-(2-benzoxazolon-3-ylacetamido)desacetoxycephalosporanic acid Chemical MeSH Prohlížeč

7-(4-carboxybutanamido)cephalosporin mustard Chemical MeSH Prohlížeč

7--((2-aminothiazol-4-yl)methoximinoacetylamino)-1-carba(1-dethia)-3-(2-(1-methyl-3-pyridyl)thiazol-4-yl)-3-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-amino-3-methyl-delta(3)-cephem-4-carboxylic acid Chemical MeSH Prohlížeč

7-amino-3-thiomethyl-3-cephalosporanic acid Chemical MeSH Prohlížeč

7-aminoacetoxycephalosporanic acid Chemical MeSH Prohlížeč

7-aminocephalosporanic acid Chemical MeSH Prohlížeč

7-aminocephalosporin doxorubicin-poly(ethylene glycol)propionic acid N-hydroxysuccinimide ester Chemical MeSH Prohlížeč

7-aminodesacetoxycephalosporanic acid Chemical MeSH Prohlížeč

7-bromoacetyl aminocephalosporanic acid Chemical MeSH Prohlížeč

7-methoxycephalosporin C Chemical MeSH Prohlížeč

7-phenylacetamidodeacetoxycephalosporanic acid Chemical MeSH Prohlížeč

7-tert-butoxycarbonylamino-2-ketocarbacepham Chemical MeSH Prohlížeč

A 27223 Chemical MeSH Prohlížeč

A1-226 Chemical MeSH Prohlížeč