Clotrimazole [klotrimazol]
- Terms
-
Bay b 5097
Canesten
FB b 5097
Kanesten
Klotrimazole
Lotrimin
Mycelex
An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.
- DUI
- D003022 MeSH Browser
- CUI
- M0004642
- CAS
- 1H-Imidazole, 1-((2-chlorophenyl)diphenylmethyl)-
- Previous indexing
- Imidazoles (1971-1974); Trityl Compounds (1974)
- History note
- 91(75); was see under IMIDAZOLES 1975-90
- Public note
- 91; was see under IMIDAZOLES 1975-90
Allowable subheadings
- AD
- administration & dosage 14
- AE
- adverse effects 2
- AG
- agonists
- AA
- analogs & derivatives 2
- AN
- analysis 4
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 3
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics 1
- PD
- pharmacology 15
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 25
- TO
- toxicity 1
- UR
- urine
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