Complement Pathway, Alternative [alternativní dráha komplementu]

topical
11
Terms

alternativní cesta aktivace komplementu
alternativní dráha aktivace komplementu
komplement - alternativní dráha
properdinová cesta
properdinová dráha

 

Alternative Complement Activation Pathway
Alternative Complement Pathway
Complement Activation Pathway, Alternative
Properdin Pathway

Persistent link   https://www.medvik.cz/link/D003170
Definition

Complement activation initiated by the interaction of microbial ANTIGENS with COMPLEMENT C3B. When COMPLEMENT FACTOR B binds to the membrane-bound C3b, COMPLEMENT FACTOR D cleaves it to form alternative C3 CONVERTASE (C3BBB) which, stabilized by COMPLEMENT FACTOR P, is able to cleave multiple COMPLEMENT C3 to form alternative C5 CONVERTASE (C3BBB3B) leading to cleavage of COMPLEMENT C5 and the assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.

DUI
D003170 MeSH Browser
CUI
M0004922
Previous indexing
Complement (1966-1978); Complement Fixation Tests (1966-1978)
History note
91(79); was see under COMPLEMENT ACTIVATION 1979-90
Public note
91; was see under COMPLEMENT ACTIVATION 1979-90

Allowable subheadings

DE
drug effects 1
ES
ethics 0
GE
genetics 2
IM
immunology 6
PH
physiology 1
RE
radiation effects 0

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G03 Metabolic Phenomena obsolete
G04 Cell Physiological Phenomena 514
G05 Genetic Phenomena 135
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 16
G12 Immune System Phenomena 248
G12.274 Complement Activation 95
G12.274.695 Complement Pathway, Alternative 11
G12.274.698 Complement Pathway, Classical 6
G12.274.849 Complement Pathway, Mannose-Binding Lectin 7
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 147
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 129
G17 Mathematical Concepts 66

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