Dapsone [dapson]
- Terms
-
Disulone
-
4,4'-Diaminophenyl Sulfone
Avlosulfone
DADPS
Dapsoderm-X
Dapson-Fatol
Diaminodiphenylsulfone
Diaphenylsulfone
Disulone
Sulfona
Sulfonyldianiline
A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
- DUI
- D003622 MeSH Browser
- CUI
- M0005661
Allowable subheadings
- AD
- administration & dosage 21
- AE
- adverse effects 13
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics 2
- PD
- pharmacology 13
- PO
- poisoning 1
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 29
- TO
- toxicity
- UR
- urine
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