One of the cytotoxic dihalohexitols that alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in a disruption of DNA function and cell cycle arrest. It has antineoplastic activity and also causes bone marrow toxicity.

DUI

D003961 MeSH Browser

CUI

M0006206

CAS

Galactitol, 1,2:5,6-dianhydro-

Previous indexing

Alcohols (1966-1971); Dulcitol (1972-1978); Ethers, Cyclic (1966-1978)

History note

91(79); was see under SUGAR ALCOHOLS 1979-90

Public note

91; was see under SUGAR ALCOHOLS 1979-90