DNA, Circular [kruhová DNA]
- Terms
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cirkulární DNA
cyklická DNA
DNA cyklická
DNA kruhová
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Circular DNA
Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992)
- Annotation
- IM; /drug eff /ultrastruct permitted
- DUI
- D004270 MeSH Browser
- CUI
- M0006682
- Previous indexing
- DNA (1966-1972)
- History note
- 74(73)
- Public note
- 74
Allowable subheadings
- AD
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- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 3
- AI
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- BI
- biosynthesis 1
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 3
- CL
- classification 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 5
- HI
- history 0
- IM
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- IP
- isolation & purification 1
- ME
- metabolism 6
- PK
- pharmacokinetics 0
- PD
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- PH
- physiology 3
- PO
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- ST
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- SD
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- TU
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- TO
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- UR
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