DNA, Circular [kruhová DNA]
- Terms
-
cirkulární DNA
cyklická DNA
DNA cyklická
DNA kruhová
-
Circular DNA
Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992)
- Annotation
- IM; /drug eff /ultrastruct permitted
- DUI
- D004270 MeSH Browser
- CUI
- M0006682
- Previous indexing
- DNA (1966-1972)
- History note
- 74(73)
- Public note
- 74
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis 3
- AI
- antagonists & inhibitors
- BI
- biosynthesis 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 3
- CL
- classification
- DE
- drug effects
- EC
- economics
- GE
- genetics 5
- HI
- history
- IM
- immunology
- IP
- isolation & purification 1
- ME
- metabolism 6
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 3
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine