Doxepin [doxepin]
- Terms
-
Aponal
doxepin hydrochlorid
Sinequan
-
Apo-Doxepin
Aponal
Deptran
Desidox
Doneurin
Doxepia
Doxepin beta
Doxepin Hydrochloride
Doxepin Hydrochloride, Cis-Trans Isomer Mixture (approximately 1:5)
Doxepin-RPh
Espadox
Mareen
Novo-Doxepin
Prudoxin
Quitaxon
Sinequan
Sinquan
Xepin
Zonalon
A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
- DUI
- D004316 MeSH Browser
- CUI
- M0006782
- CAS
- 1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N,N-dimethyl-
- History note
- 74
- Public note
- 74
Allowable subheadings
- AD
- administration & dosage 2
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics 1
- PD
- pharmacology 2
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 3
- TO
- toxicity
- UR
- urine