Glykosidáza, která hydrolyzuje glukosylceramid za vzniku volného ceramidu a glukózy. Deficit tohoto enzymu vede u Gaucherovy nemoci k abnormálně vysokým koncentracím glukosylceramidu v mozku. EC 3.2.1.45.

A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.

Anotace

/defic: consider also GAUCHER DISEASE

DUI

D005962 MeSH Prohlížeč

CUI

M0009360

CAS

D-Glucosyl-N-acylsphingosine glucosylhydrolase

Předchozí užití

Glucose (1970-1974); Cerebrosides (1970-1974); Glycoside Hydrolases (1970-1974)

Historická pozn.

91(75); was see under GLUCOSIDASES 1975-90

Veřejná pozn.

91; was see under GLUCOSIDASES 1975-90