1,4-alpha-D-Glucan-1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase/dextrin 6 alpha-D-glucanohydrolase. An enzyme system having both 4-alpha-glucanotransferase (EC 2.4.1.25) and amylo-1,6-glucosidase (EC 3.2.1.33) activities. As a transferase it transfers a segment of a 1,4-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or another 1,4-alpha-D-glucan. As a glucosidase it catalyzes the endohydrolysis of 1,6-alpha-D-glucoside linkages at points of branching in chains of 1,4-linked alpha-D-glucose residues. Amylo-1,6-glucosidase activity is deficient in glycogen storage disease type III.

Annotation

/defic: consider also GLYCOGEN STORAGE DISEASE TYPE III

DUI

D006004 MeSH Browser

CUI

M0009460

Previous indexing

Glucosidase (1973-1975); Glucosyltransferases (1973-1975); Glycogen (1973-1975)

History note

89(76); was GLYCOGEN DEBRANCHING ENZYME see under GLUCOSYLTRANSFERASES 1976-88

Online note

use GLYCOGEN DEBRANCHING ENZYME SYSTEM to search GLYCOGEN DEBRANCHING ENZYME 1976-88

Public note

89; was GLYCOGEN DEBRANCHING ENZYME see under GLUCOSYLTRANSFERASES 1976-88