Guanylyl Imidodiphosphate [guanylylimidodifosfát]
- Terms
-
GMP-P(NH)P
GMP-PNP
Gpp(NH)p
Guanosine 5'-(Beta,Gamma-Imido)Triphosphate
Guanyl-5'-Imidodiphosphate
P(NH)PPG
A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of ADENYLYL CYCLASES.
- DUI
- D006165 MeSH Browser
- CUI
- M0009703
- CAS
- 5'-Guanylic acid, monoanhydride with imidodiphosphoric acid
- Previous indexing
- Guanine Nucleotides (1966-1977); Guanosine Triphosphate (1972-1977)
- History note
- 91(78); was see under GUANOSINE TRIPHOSPHATE 1978-90
- Public note
- 91; was see under GUANOSINE TRIPHOSPHATE 1978-90
Allowable subheadings
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- administration & dosage
- AE
- adverse effects
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- AA
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- analysis
- AI
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- chemistry
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- immunology
- IP
- isolation & purification
- ME
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- PK
- pharmacokinetics
- PD
- pharmacology 3
- PO
- poisoning
- RE
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- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UR
- urine
N(2)-(4-n-butylphenyl)-2'--deoxyguanosine 5'-imidotriphosphate Chemical MeSH Browser