Leukotrienes [leukotrieny]

topical
158
Terms

Leukotriene

Persistent link   https://www.medvik.cz/link/D015289
Definition

A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.

Annotation
general or unspecified; prefer specifics
DUI
D015289 MeSH Browser
CUI
M0023536
Previous indexing
Arachidonic Acids (1979-1988); Leukotrienes B (1983-1988); SRS-A (1979-1988)
History note
89
Public note
89

Combination

antagonists & inhibitors
Leukotriene Antagonists

Allowable subheadings

AD
administration & dosage 9
AE
adverse effects 9
AG
agonists
AN
analysis 23
BI
biosynthesis 14
BL
blood 6
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 6
CL
classification 2
DF
deficiency 1
EC
economics
GE
genetics 1
HI
history 2
IM
immunology 7
IP
isolation & purification 2
ME
metabolism 15
PK
pharmacokinetics 3
PD
pharmacology 17
PH
physiology 11
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 28
TO
toxicity 1
UR
urine 3

D Chemicals and Drugs
D10 Lipids 2 528
D10.251 Fatty Acids 1 433
D10.251.355 Fatty Acids, Unsaturated 474
D10.251.355.255 Eicosanoids 96
D10.251.355.255.100 Arachidonic Acids 118
D10.251.355.255.100.100 Arachidonic Acid 125
D10.251.355.255.100.300 Hydroxyeicosatetraenoic Acids 14
D10.251.355.255.100.375 Isoprostanes 14
D10.251.355.255.100.450 Leukotrienes 158
D10.251.355.255.100.450.405 Leukotriene A4 1
D10.251.355.255.100.450.411 Leukotriene B4 13
D10.251.355.255.100.450.855 SRS-A 9
D10.251.355.255.100.825 Thromboxanes 23
D10.251.355.310 Fatty Acids, Essential 114
D10.251.355.310.166 Arachidonic Acids 118
D10.251.355.310.166.100 Arachidonic Acid 125
D10.251.355.310.166.550 Hydroxyeicosatetraenoic Acids 14
D10.251.355.310.166.775 Isoprostanes 14
D10.251.355.310.166.887 Leukotrienes 158
D10.251.355.310.166.887.405 Leukotriene A4 1
D10.251.355.310.166.887.411 Leukotriene B4 13
D10.251.355.310.166.887.855 SRS-A 9
D10.251.355.310.166.971 Thromboxanes 23
D23 Biological Factors 143
D23.469 Inflammation Mediators 325
D23.469.050 Autacoids 3
D23.469.050.175 Eicosanoids 96
D23.469.050.175.450 Leukotrienes 158
D23.469.050.175.450.400 Leukotriene A4 1
D23.469.050.175.450.415 Leukotriene B4 13
D23.469.050.175.450.725 SRS-A 9
D23.469.050.175.725 Prostaglandins 665

12-HPETE Chemical MeSH Browser

14,15-dihydroperoxyeicosatetraenoic acid Chemical MeSH Browser

15-hydroperoxy-5,8,11,13-eicosatetraenoic acid Chemical MeSH Browser

15-hydroperoxy-5,9,11,13-eicosatetraenoic acid Chemical MeSH Browser

5,15-dihydroperoxyeicosatetraenoic acid Chemical MeSH Browser

5-hydroxy-6-(2-keto-3-thiopropionyl)-7,9,11,14-eicosatetraenoic acid Chemical MeSH Browser

8,15-diHPETE Chemical MeSH Browser

8-hydroperoxyeicosatetraenoic acid Chemical MeSH Browser

arachidonic acid 5-hydroperoxide Chemical MeSH Browser

cysteinyl-leukotriene Chemical MeSH Browser

eoxin C4 Chemical MeSH Browser

leukotriene E5 Chemical MeSH Browser

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