SRS-A [SRS-A]
- Terms
-
pomalu reagující substance anafylaxe
-
Slow Reacting Substance of Anaphylaxis
A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a slow-reacting substance of ANAPHYLAXIS released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed)
- Annotation
- /biosyn /physiol permitted
- DUI
- D013189 MeSH Browser
- CUI
- M0020404
- Previous indexing
- Muscle, Smooth/physiology (1966); Anaphylaxis (1966)
- History note
- 73(67)
- Public note
- 73
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives 1
- AN
- analysis 1
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UR
- urine