Isoprostanes [isoprostany]
- Terms
-
isoprostan
-
Isoprostane
A series of prostaglandin-like compounds that are produced by the attack of free-radical species on unsaturated fatty acids, especially ARACHIDONIC ACID, of cellular MEMBRANES. Once cleaved from the lipid membrane by the action of phospholipases they can circulate into various bodily fluids and eventually be excreted. Although these compounds resemble enzymatically synthesized prostaglandins their stereoisometric arrangement is usually different than the naturally occurring compounds.
- DUI
- D028421 MeSH Browser
- CUI
- M0382190
- Previous indexing
- Dinoprost (1992-2001); Lipid Peroxides (1992-2001)
- History note
- 2002
- Public note
- 2002
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects 1
- AG
- agonists
- AN
- analysis 3
- AI
- antagonists & inhibitors
- BI
- biosynthesis 1
- BL
- blood 4
- CF
- cerebrospinal fluid
- CS
- chemical synthesis 1
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification 1
- ME
- metabolism 5
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity 1
- UR
- urine 1
1-palmitoyl-2-(epoxyisoprostane-E2)-sn-glycero-3-phosphocholine Chemical MeSH Browser
15-F2alpha-isoprostane Chemical MeSH Browser
4-(3-((3-hydroxy-2-(oct-2-enyl)-5-oxocyclopentylidene)methyl)oxiran-2-yl)butanoic acid Chemical MeSH Browser
5,6-epoxyisoprostane E2 Chemical MeSH Browser
8,12-iso-iPF3alpha-VI Chemical MeSH Browser
8-isoprostaglandin A1 Chemical MeSH Browser
8-isoprostaglandin E2 Chemical MeSH Browser
8-isoprostaglandin F1alpha Chemical MeSH Browser
A(2) isoprostane Chemical MeSH Browser
epoxyisoprostane EC Chemical MeSH Browser
epoxyisoprostane EI Chemical MeSH Browser
isoprostane F2alpha III Chemical MeSH Browser