The class of heavy chains found in IMMUNOGLOBULIN M. They have a molecular weight of approximately 72 kDa and they contain about 57 amino acid residues arranged in five domains and have more oligosaccharide branches and a higher carbohydrate content than the heavy chains of IMMUNOGLOBULIN G.

Annotation

gammopathy: coordinate IMMUNOGLOBULIN MU-CHAINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM) or HEAVY CHAIN DISEASE (IM), follow text; for immunoglobulin C mu (IG C mu) coordinate with IMMUNOGLOBULIN CONSTANT REGION

DUI

D007148 MeSH Browser

CUI

M0011144

Previous indexing

Immunoglobulin Fragments (1973-1975); Immunoglobulins, Heavy Chain (1975); IgM (1973-1975)

History note

2006 (1976)

Public note

2006; see IMMUNOGLOBULINS, MU-CHAIN 1992-2005, see IMMUNOGLOBULINS, MU CHAIN 1987-1991, see IMMUNOGLOBULINS, HEAVY CHAIN 1976-1986