Langerhansovy ostrůvky - malé ostrůvky buněk s endokrinní funkcí roztroušené uvnitř slinivky břišní, která jich obsahuje cca 1-2 miliony. Existují v nich tři typy buněk (alfa, beta, delta, resp. A, B, D). L. o. produkují několik hormonů, zejm. inzulin (beta buňky), glukagon (alfa buňky), somatostatin (delta buňky). (cit. Velký lékařský slovník online 2012, http://lekarske.slovniky.cz/)

Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.

Anotace

do not confuse with LANGERHANS CELLS (skin); neoplasms = ADENOMA, ISLET CELL or CARCINOMA, ISLET CELL or their specifics

DUI

D007515 MeSH Prohlížeč

CUI

M0011741

Historická pozn.

91; was ISLANDS OF LANGERHANS 1963-90

Online pozn.

use ISLETS OF LANGERHANS to search ISLANDS OF LANGERHANS 1966-90

Veřejná pozn.

91; was ISLANDS OF LANGERHANS 1963-90