Islets of Langerhans [Langerhansovy ostrůvky]
- Terms
-
Islands of Langerhans
Islet Cells
Nesidioblasts
Pancreas, Endocrine
Pancreatic Islets
Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
- Annotation
- do not confuse with LANGERHANS CELLS (skin); neoplasms = ADENOMA, ISLET CELL or CARCINOMA, ISLET CELL or their specifics
- DUI
- D007515 MeSH Browser
- CUI
- M0011741
- History note
- 91; was ISLANDS OF LANGERHANS 1963-90
- Online note
- use ISLETS OF LANGERHANS to search ISLANDS OF LANGERHANS 1966-90
- Public note
- 91; was ISLANDS OF LANGERHANS 1963-90
Combination
- transplantation
- Islets of Langerhans Transplantation
Allowable subheadings
- AB
- abnormalities 0
- AH
- anatomy & histology 9
- BS
- blood supply 3
- CH
- chemistry 0
- CY
- cytology 37
- DG
- diagnostic imaging 3
- DE
- drug effects 25
- EM
- embryology 2
- EN
- enzymology 2
- GD
- growth & development 4
- IM
- immunology 41
- IN
- injuries 1
- IR
- innervation 0
- ME
- metabolism 26
- MI
- microbiology 0
- PS
- parasitology 0
- PA
- pathology 29
- PH
- physiology 25
- PP
- physiopathology 23
- RE
- radiation effects 0
- SU
- surgery 4
- UL
- ultrastructure 9
- VI
- virology 1